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基于磁性粒子的生物传感器和生物分析器件:综述。

Biosensors and Bioanalytical Devices based on Magnetic Particles: A Review.

机构信息

Faculty of Military Health Sciences, University of Defense, Trebesska 1575, Hradec Kralove CZ-50001, Czech Republic.

出版信息

Curr Med Chem. 2021;28(14):2828-2841. doi: 10.2174/0929867327666200730213721.

DOI:10.2174/0929867327666200730213721
PMID:32744958
Abstract

Magnetic particles play an important role in current technology, and this field of technology extends to a broader progression. The term magnetic particles typically cover the paramagnetic particles and super-paramagnetic particles. Various materials like iron oxide are common, but other materials are available as well; a survey of such materials has been included in this work. They can serve for technological purposes like separation and isolation of chemical products or toxic waste, their use in the diagnosis of pathologies, drug delivery and other similar applications. In this review, biosensors, bioanalytical devices and bioassays, have been discussed. Materials for magnetic particles preparation, methods of assay, biosensors and bioassays working in stationary as well as flow-through arrangements are described here. A survey of actual literature has been provided as well.

摘要

磁性粒子在当前技术中扮演着重要的角色,并且这个技术领域还在不断扩展。磁性粒子这个术语通常涵盖顺磁性粒子和超顺磁性粒子。氧化铁等各种材料很常见,但也有其他材料可用;这项工作包括了对这些材料的调查。它们可用于技术目的,如化学产品或有毒废物的分离和隔离,在病理学诊断、药物输送和其他类似应用中也有应用。在这篇综述中,讨论了生物传感器、生物分析装置和生物测定。这里描述了用于磁性粒子制备的材料、测定方法、在固定和流动装置中工作的生物传感器和生物测定。也提供了对实际文献的调查。

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