Department of Nutritional Sciences, School of Life Course Sciences, King's College London, Franklin-Wilkins-Building, 150 Stamford Street, London SE1 9NH, UK.
Department of Nutritional Sciences, School of Life Course Sciences, King's College London, Franklin-Wilkins-Building, 150 Stamford Street, London SE1 9NH, UK.
Food Chem. 2021 Jan 15;335:127671. doi: 10.1016/j.foodchem.2020.127671. Epub 2020 Jul 28.
Iron deficiency anaemia (IDA) is a common nutritional disorder worldwide. Sustainable food-based approaches are being advocated to use high and bioavailable dietary iron sources to prevent iron deficiency. The study investigated the bioaccessibility and bioavailability of iron from some plant products. Total iron levels in the samples were measured by inductively coupled plasma optical emission spectrometry (ICP-OES). Fractionation of the iron from the digested extracts was carried out by centrifugation and ultrafiltration. Iron bioavailability was determined using an in vitro simulated peptic-pancreatic digestion, followed by measurement of ferritin in Caco-2 cells. The highest amount of bioaccessible iron was obtained from moringa leaves (9.88% ± 0.45 and 8.44 ± 0.01 mg/100 g), but the highest percentage bioavailability was from baobab fruit pulp (99.7% ± 0.13 and 1.74 ± 0.01 mg/100 g) respectively. All the plant products, except for baobab, significantly inhibited iron uptake from FeSO and FAC, with fenugreek sprout being the most inhibitory.
缺铁性贫血（IDA）是全球范围内常见的营养失调。人们提倡可持续的基于食物的方法，利用高生物可利用的饮食铁源来预防缺铁。本研究调查了一些植物产品中铁的生物可利用性和生物有效性。样品中的总铁含量通过电感耦合等离子体光学发射光谱法（ICP-OES）进行测量。通过离心和超滤对消化提取物中的铁进行分级。使用体外模拟胃蛋白酶-胰酶消化，然后测量 Caco-2 细胞中的铁蛋白，来确定铁的生物有效性。从辣木叶中获得的可生物利用铁量最高（9.88%±0.45 和 8.44%±0.01 mg/100 g），但从猴面包树果肉中获得的铁生物有效性百分比最高（99.7%±0.13 和 1.74%±0.01 mg/100 g）。除了猴面包树之外，所有植物产品均显著抑制 FeSO 和 FAC 中铁的吸收，其中胡芦巴芽的抑制作用最强。
