Zee Phyllis C, Abbott Sabra M
Continuum (Minneap Minn). 2020 Aug;26(4):988-1002. doi: 10.1212/CON.0000000000000884.
This article provides an overview of circadian physiology and discusses common presentations and treatment strategies for the circadian rhythm sleep-wake disorders.
Circadian rhythms are present throughout the body, and appreciation for the role that circadian dysregulation plays in overall health is increasing, with mounting associations between circadian disruption and cardiometabolic disease risk.
It is important to recognize the ubiquitous role that circadian rhythms play throughout the brain and body. An understanding of circadian neurophysiology will provide insight into the means by which patients with a variety of neuropathologies at the level of the retina, optic nerve, or hypothalamus may also be at risk for circadian dysfunction.
本文概述昼夜节律生理学,并讨论昼夜节律性睡眠-觉醒障碍的常见表现及治疗策略。
昼夜节律遍布全身,随着昼夜节律失调与心血管代谢疾病风险之间的关联日益增多,人们越来越认识到昼夜节律失调在整体健康中所起的作用。
认识到昼夜节律在大脑和身体中普遍存在的作用很重要。了解昼夜节律神经生理学将有助于深入了解视网膜、视神经或下丘脑水平存在各种神经病理学的患者也可能面临昼夜节律功能障碍风险的方式。