From the Department of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Department of Psychiatry, Washington University, St Louis, Missouri, USA.
Alcohol Clin Exp Res. 2020 Sep;44(9):1852-1861. doi: 10.1111/acer.14412. Epub 2020 Aug 6.
Aggression often occurs alongside alcohol and drug misuse. However, it is not clear whether the latent and manifest relations among alcohol-related, drug-related, and non-substance-related aggression are separate manifestations of a single construct or instead are 3 distinct constructs.
To examine these associations, we conducted a preregistered analysis of 13,490 participants in the Collaborative Study on the Genetics of Alcoholism. In a structured interview, participants reported their lifetime perpetration of these 3 aggression phenotypes.
The data were better fit by a model that treated these aggression phenotypes as 3 distinct latent factors, as compared to models in which the items all loaded onto 1 ("general") or 2 ("substance-related" and "non-substance-related") aggression factors. This 3-factor model fit better for men than women. Subsequent exploratory analyses then showed that among these 3 factors, alcohol-related aggression explained the variance of overall aggression better than the other 2 factors.
Our findings suggest that these 3 forms of aggression are distinct phenotypes (especially among men). Yet, people's alcohol-related aggression can accurately characterize their overall aggressive tendencies across these domains. Future research will benefit from articulating the unique and shared pathways and risk factors underlying each of these facets of aggression.
攻击性常常伴随着酗酒和吸毒行为出现。然而，目前尚不清楚酒精相关、药物相关和非物质相关的攻击性之间的潜在和明显关系是单一结构的不同表现，还是 3 种不同的结构。
为了检验这些关联，我们对酗酒遗传学合作研究中的 13490 名参与者进行了预先注册的分析。在结构化访谈中，参与者报告了他们一生中对这 3 种攻击性表现的实施情况。
与将这些攻击性表现视为 3 个独立潜在因素的模型相比，将项目全部加载到 1 个（“一般”）或 2 个（“物质相关”和“非物质相关”）攻击性因素的模型对数据的拟合更好。与女性相比，这种 3 因素模型更适合男性。随后的探索性分析表明，在这 3 个因素中，酒精相关的攻击性比其他 2 个因素更好地解释了总体攻击性的差异。
我们的研究结果表明，这 3 种形式的攻击性是不同的表现形式（尤其是男性）。然而，人们的酒精相关攻击性可以准确描述他们在这些领域的整体攻击性倾向。未来的研究将受益于阐明这些攻击性特征的每个方面背后的独特和共同途径和风险因素。
