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人类包虫病的免疫学诊断

The immunological diagnosis of human hydatid disease.

作者信息

Matossian R M

出版信息

Trans R Soc Trop Med Hyg. 1977;71(2):101-4. doi: 10.1016/0035-9203(77)90070-0.

Abstract

There is evidence that the yearly incidence rate of hydatid disease may be increasing in endemic areas and in regions of the world hitherto free of the infection. The availability of an accurate method of detection in both man and other animals would facilitate understanding of the global epidemiology. The diagnostic procedures in use in human hydatidosis have often given inconclusive results in animal infections. The following tests are discussed and their usefulness appraised: intradermal, complement fixation, haemagglutination, latex agglutination, indirect fluorescent antibody, immunoelectrophoresis, counter immunoelectrophoresis, enzyme linked immunosorbent assay, radio-immuno assay and lymphocyte transformation.

摘要

有证据表明,在地方性流行地区以及世界上迄今尚无该感染的区域,包虫病的年发病率可能正在上升。在人类和其他动物中都具备一种准确的检测方法,将有助于了解全球流行病学情况。目前用于人类包虫病的诊断程序在动物感染中常常得出不确定的结果。本文讨论了以下检测方法并评估了它们的实用性:皮内试验、补体结合试验、血凝试验、乳胶凝集试验、间接荧光抗体试验、免疫电泳、对流免疫电泳、酶联免疫吸附测定、放射免疫测定以及淋巴细胞转化试验。

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