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通过在高风险地区增加产前检测发现德克萨斯州伊达尔戈县的本地寨卡病毒疫情。

Detection of a Locally-Acquired Zika Virus Outbreak in Hidalgo County, Texas through Increased Antenatal Testing in a High-Risk Area.

作者信息

Hinojosa Steven, Alquiza Alexander, Guerrero Clarissa, Vanegas Diana, Tapangan Niko, Cano Narda, Olivarez Eduardo

机构信息

Hidalgo County Health and Human Services Department, Edinburg, TX 78542, USA.

出版信息

Trop Med Infect Dis. 2020 Aug 5;5(3):128. doi: 10.3390/tropicalmed5030128.

Abstract

Hidalgo County (HC), located along the Texas-Mexico border, was listed as a high-risk county for Zika virus (ZIKV) in 2017 by the Texas Department of State Health Services, based on its historical presence of Dengue. Due to its subtropical climate, active binational travel, and population of low socioeconomic status, Hidalgo County focused on disease detection activities for the prevention of further transmission. Therefore, Hidalgo County Health and Human Services enacted public health surveillance, reviewed laboratory results, and conducted epidemiological investigations from 2016 to 2018. In 2017, Hidalgo County experienced a locally-acquired outbreak of Zika virus disease, resulting in the highest local mosquito-borne acquisition case count for the year within the United States. This resulted in Hidalgo County reviewing epidemiological data for disease detection and risk areas. With the data review, key outcomes of testing were identified. This included the importance of both RT-PCR and IgM-ELISA/PRNT testing methods. In addition, increased antenatal testing and surveillance also recognized the need of improved disease identification and testing among the general population, especially during localized outbreaks.

摘要

伊达尔戈县(HC)位于得克萨斯州与墨西哥边境沿线,由于历史上曾有登革热疫情,2017年被得克萨斯州州立卫生服务部列为寨卡病毒(ZIKV)高风险县。由于其亚热带气候、活跃的双边旅行以及社会经济地位较低的人口,伊达尔戈县重点开展疾病检测活动以防止进一步传播。因此,伊达尔戈县卫生与公众服务部在2016年至2018年期间实施了公共卫生监测,审查实验室结果,并进行了流行病学调查。2017年,伊达尔戈县出现了本地传播的寨卡病毒病疫情,成为当年美国境内本地蚊虫传播感染病例数最多的地区。这促使伊达尔戈县审查疾病检测和风险区域的流行病学数据。通过数据审查,确定了检测的关键结果。这包括逆转录聚合酶链反应(RT-PCR)和免疫球蛋白M酶联免疫吸附测定/蚀斑减少中和试验(IgM-ELISA/PRNT)检测方法的重要性。此外,增加产前检测和监测也认识到在普通人群中,尤其是在局部疫情期间,需要改进疾病识别和检测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bd17/7558844/50e90213ac2b/tropicalmed-05-00128-g001.jpg

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