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与冠状病毒感染(COVID-19)相关的嗅觉丧失和味觉丧失——目前已知哪些情况?

Anosmia and ageusia associated with coronavirus infection (COVID-19) - what is known?

作者信息

Tanasa Ingrid Andrada, Manciuc Carmen, Carauleanu Alexandru, Navolan Dan Bogdan, Bohiltea Roxana Elena, Nemescu Dragos

机构信息

Department of Obstetrics and Gynecology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

Department of Infectious Diseases, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

出版信息

Exp Ther Med. 2020 Sep;20(3):2344-2347. doi: 10.3892/etm.2020.8808. Epub 2020 May 28.

Abstract

In 2020 a new pandemic caused by the SARS-CoV-2 coronavirus is affecting the lives of millions of patients and healthcare workers worldwide. The clinical picture of this infection is in a dynamic process of discovery, and more symptoms emerge as the clinicians observe and diagnose manifestations that affect multiple organs. Anosmia (loss of smell), and ageusia (loss of taste) become more frequently cited as independent symptoms or in association with the most common manifestations of the disease, such as fever, cough and dyspnea. A thorough screening program will prevent most nosocomial and community-acquired infections by promoting efficient triage and specific measures such as isolation of the patients. Therefore, it is important to include frequent symptoms in the anamnesis and questionnaires to select those patients who might benefit from testing, isolation, and treatment. This study summarizes the existing data regarding the association of anosmia and ageusia with the SARS-CoV-2 infection. It also aims to describe manifestations of these, particularly in the clinical picture of all symptomatic patients.

摘要

2020年,由严重急性呼吸综合征冠状病毒2(SARS-CoV-2)引发的一场新的大流行病正在影响全球数百万患者和医护人员的生活。这种感染的临床症状正处于一个动态的发现过程中,随着临床医生观察和诊断出影响多个器官的表现,更多症状不断出现。嗅觉丧失(嗅觉减退)和味觉丧失(味觉减退)越来越多地被作为独立症状或与该疾病的最常见表现(如发热、咳嗽和呼吸困难)相关联而被提及。一个全面的筛查计划将通过促进有效的分诊以及采取隔离患者等具体措施来预防大多数医院获得性感染和社区获得性感染。因此,在问诊和问卷中纳入常见症状对于挑选出那些可能从检测、隔离和治疗中受益的患者很重要。本研究总结了关于嗅觉丧失和味觉丧失与SARS-CoV-2感染之间关联的现有数据。它还旨在描述这些症状的表现,尤其是在所有有症状患者的临床症状方面。

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