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产前眼球突出提示产后眼眶畸胎瘤。

Prenatal Exophthalmia Revealing a Postnatal Orbital Teratoma.

作者信息

Ahnoux-Zabsonre Ahgbatouhabeba, Sanou Jérôme, Lankoandé Yérénou Ferdinand, Bouda Chantal, Méda Gertrude, Lamien-Sanou Assita

机构信息

UFR/SDS University Joseph Ki Zerbo, 03 BP7021, Ouagadougou, Burkina Faso.

Yalgado Ouedraogo University Hospital Center, Department of Ophthalmology, 03 BP7022, Captain Sankara Avenue, Ouagadougou, Burkina Faso.

出版信息

Case Rep Ophthalmol Med. 2020 Jul 13;2020:1597353. doi: 10.1155/2020/1597353. eCollection 2020.

DOI:10.1155/2020/1597353
PMID:32765918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7374210/
Abstract

PURPOSE

Teratomas are congenital tumors of stem cells derived from the three germ layers. They are frequently located in the sacrococcygeal region. Orbital teratoma is rare with less than 70 cases reported until 2016. We report the case of prenatal exophthalmia discovered by ultrasound exam which turned out to be a teratoma postnatally. The newborn in our case was female, just as described in the literature. Treatment consisted of total removal of the teratoma and the eyeball. Reconstructive surgery remains a big challenge since our medical technology is limited.

CONCLUSION

A prenatal exophthalmia on fetal ultrasound should make us think of a teratoma, even if it is very rare. Fetal orbital teratoma may be associated with fetal survival. The infant will benefit from a reconstructive surgery of the orbit.

摘要

目的

畸胎瘤是源自三个胚层的干细胞先天性肿瘤。它们常位于骶尾部区域。眼眶畸胎瘤罕见,截至2016年报道的病例不足70例。我们报告了一例产前超声检查发现眼球突出,出生后证实为畸胎瘤的病例。我们病例中的新生儿为女性,正如文献中所描述的那样。治疗包括畸胎瘤和眼球的完全切除。由于我们的医疗技术有限,重建手术仍然是一个巨大的挑战。

结论

胎儿超声检查发现的产前眼球突出应使我们想到畸胎瘤,即使其非常罕见。胎儿眼眶畸胎瘤可能与胎儿存活有关。婴儿将从眼眶重建手术中获益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/981480971047/CRIOPM2020-1597353.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/dc5c0fd393ed/CRIOPM2020-1597353.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/5abacc56d4af/CRIOPM2020-1597353.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/b4921c6864b0/CRIOPM2020-1597353.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/981480971047/CRIOPM2020-1597353.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/dc5c0fd393ed/CRIOPM2020-1597353.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/5abacc56d4af/CRIOPM2020-1597353.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/b4921c6864b0/CRIOPM2020-1597353.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d761/7374210/981480971047/CRIOPM2020-1597353.004.jpg

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本文引用的文献

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Orbital immature teratoma: A rare entity with diagnostic challenges.眼眶未成熟畸胎瘤:一种具有诊断挑战性的罕见实体。
Saudi J Ophthalmol. 2018 Jan-Mar;32(1):75-78. doi: 10.1016/j.sjopt.2017.12.005. Epub 2018 Jan 11.
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Orbital Teratoma: A rare congenital tumour.眼眶畸胎瘤:一种罕见的先天性肿瘤。
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Congenital Orbital Teratoma.
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Mature teratoma presenting as orbital cellulitis in a 5-month-old baby.一名5个月大婴儿出现眼眶蜂窝织炎,病因是成熟畸胎瘤。
Ann Saudi Med. 2013 Nov-Dec;33(6):623-6. doi: 10.5144/0256-4947.2013.623.
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Congenital orbital teratoma.先天性眼眶畸胎瘤。
Indian J Ophthalmol. 2013 Dec;61(12):767-9. doi: 10.4103/0301-4738.111219.
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Congenital orbital teratoma: a case report and challenges of its management in a resource limited setting.先天性眼眶畸胎瘤:一例报告及其在资源有限环境下的管理挑战
Pan Afr Med J. 2012;12:3. Epub 2012 May 4.
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Antenatally diagnosed congenital orbital teratoma in which rupture was associated with intrauterine fetal death.
J Obstet Gynaecol Res. 2012 Mar;38(3):578-81. doi: 10.1111/j.1447-0756.2011.01738.x. Epub 2012 Feb 16.
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Massive congenital orbital teratoma.巨大先天性眼眶畸胎瘤。
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Mature and immature extracranial teratomas in children: the UK Children's Cancer Study Group Experience.儿童成熟和未成熟颅外畸胎瘤:英国儿童癌症研究组的经验
J Clin Oncol. 2008 Jul 20;26(21):3590-7. doi: 10.1200/JCO.2008.16.0622. Epub 2008 Jun 9.
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Prenatally detected congenital orbital teratoma.产前检测出的先天性眼眶畸胎瘤。
Ultrasound Obstet Gynecol. 2008 Jan;31(1):107-9. doi: 10.1002/uog.5140.