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初发糖尿病和新发甲状腺疾病表现为须部斑秃:一例须部斑秃病例报告及治疗回顾

Incipient Diabetes Mellitus and Nascent Thyroid Disease Presenting as Beard Alopecia Areata: Case Report and Treatment Review of Alopecia Areata of the Beard.

作者信息

Forouzan Parnia, Cohen Philip R

机构信息

Dermatology, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, USA.

Dermatology, San Diego Family Dermatology, National City, USA.

出版信息

Cureus. 2020 Jul 31;12(7):e9500. doi: 10.7759/cureus.9500.

Abstract

Alopecia areata is a non-scarring hair loss that commonly presents on the scalp. In men, when this condition results in facial hair loss on the cheek, jaw, and neck, it is referred to as beard alopecia areata. Beard alopecia areata can be associated with autoimmune conditions, such as diabetes mellitus, thyroid disorders, and vitiligo. A 28-year-old man presented with a five-month history of facial hair loss; his condition was diagnosed as beard alopecia areata after clinical examination. Treatment with twice daily topical 0.1% triamcinolone acetonide cream led to complete regrowth of his beard hair after six months. There are several potential agents and modalities for the treatment of individuals with beard alopecia areata. Treatment options include corticosteroid therapy (intralesional or topical), immunotherapy, Janus kinase (JAK) inhibitors, lasers, photodynamic therapy, platelet-rich plasma therapy, and treatment of an underlying infection. Laboratory evaluation, prompted by our patient's diagnosis of beard alopecia areata, suggested incipient diabetes mellitus and nascent thyroid disease; specifically, he had elevated fasting blood glucose and elevated thyroid-stimulating hormone levels. Therefore, in patients with beard alopecia areata, laboratory evaluation for concomitant or incipient autoimmune diseases should be considered.

摘要

斑秃是一种常见于头皮的非瘢痕性脱发。在男性中,当这种情况导致脸颊、下巴和颈部的面部毛发脱落时,称为胡须部斑秃。胡须部斑秃可能与自身免疫性疾病有关,如糖尿病、甲状腺疾病和白癜风。一名28岁男性有5个月的面部毛发脱落病史;经临床检查,其病情被诊断为胡须部斑秃。每天两次外用0.1%曲安奈德乳膏治疗6个月后,他的胡须完全重新生长。对于患有胡须部斑秃的个体,有几种潜在的治疗药物和方式。治疗选择包括皮质类固醇疗法(皮损内或外用)、免疫疗法、 Janus激酶(JAK)抑制剂、激光、光动力疗法、富血小板血浆疗法以及治疗潜在感染。根据我们这位患者的胡须部斑秃诊断进行的实验室评估提示早期糖尿病和初发甲状腺疾病;具体而言,他的空腹血糖升高且促甲状腺激素水平升高。因此,对于患有胡须部斑秃的患者,应考虑对其伴随或初发的自身免疫性疾病进行实验室评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7179/7398044/28189090e3d5/cureus-0012-00000009500-i01.jpg

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