Department of Food Science/DCA, Universidade Federal de Lavras (UFLA), Lavras, Brazil.
Department of Veterinary Medicine, Universidade Federal de Lavras, Lavras, Brazil.
J Sci Food Agric. 2021 Feb;101(3):1053-1064. doi: 10.1002/jsfa.10714. Epub 2020 Aug 28.
Nutritional intervention with the use of phytochemicals is an important method for the treatment and prevention of a metabolic syndrome. The objective of this study was to chemically characterize Moro orange juice. The influence of juice intake on metabolic parameters of rats that were obese, diabetic or both by means of body mass management after the activation of anthocyanins during refrigerated storage was also assessed.
Juice intake reversed most of the metabolic abnormalities exhibited by obese rats, including reduction of body mass and improvement of the biochemical profile. The loss of body mass by diabetic animals and obese and diabetic animals was not attributed to juice intake, but to type I diabetes mellitus. In these animals, no improvement was observed in the biochemical profile, liver enzymes and glycemia, so this treatment model was deemed unfeasible.
The beneficial effects cannot be explained only by the anthocyanin C3G present in the juice, but rather, by the synergism between all the components. Studies in humans are needed to determine whether the ingestion of this orange can be recommended as an effective strategy to prevent or ameliorate complications of obesity. © 2020 Society of Chemical Industry.
营养干预结合植物化学物质的使用是治疗和预防代谢综合征的一种重要方法。本研究的目的是对酸橘汁进行化学分析。评估了冷藏过程中花色苷激活后，摄入酸橘汁对肥胖、糖尿病或两者兼有的大鼠代谢参数的影响，这些肥胖大鼠的代谢参数可通过控制体重进行管理。
酸橘汁的摄入逆转了肥胖大鼠表现出的大多数代谢异常，包括体重减轻和生化指标的改善。糖尿病动物和肥胖及糖尿病动物的体重减轻并非归因于酸橘汁的摄入，而是 1 型糖尿病。在这些动物中，生化指标、肝酶和血糖没有得到改善，因此这种治疗模式是不可行的。
有益的效果不能仅用果汁中存在的花色苷 C3G 来解释，而是所有成分之间的协同作用。需要在人体中进行研究，以确定摄入这种酸橘汁是否可以作为预防或改善肥胖并发症的有效策略。 © 2020 英国化学学会。
