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维生素 D3 和 K2 及其降低 COVID-19 死亡率的潜在贡献。

Vitamin D3 and K2 and their potential contribution to reducing the COVID-19 mortality rate.

机构信息

Mathematical and Statistical Methods (Biometris), Wageningen University, P.O. Box 16, 6700 AA Wageningen, The Netherlands.

出版信息

Int J Infect Dis. 2020 Oct;99:286-290. doi: 10.1016/j.ijid.2020.07.080. Epub 2020 Aug 6.

DOI:10.1016/j.ijid.2020.07.080
PMID:32768697
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7406600/
Abstract

The world is desperately seeking for a sustainable solution to combat the coronavirus strain SARS-CoV-2 (COVID-19). Recent research indicated that optimizing Vitamin D blood levels could offer a solution approach that promises a heavily reduced fatality rate as well as solving the public health problem of counteracting the general vitamin D deficiency. This paper dived into the immunoregulatory effects of supplementing Vitamin D by elaborating a causal loop diagram. Together with D, vitamin K and magnesium should be supplemented to prevent long-term health risks. Follow up clinical randomized trials are required to verify the current circumstantial evidence.

摘要

全世界都在急切地寻找可持续的解决方案来对抗冠状病毒株 SARS-CoV-2（COVID-19）。最近的研究表明，优化维生素 D 血液水平可能提供一种解决方案，有望大幅降低死亡率，并解决对抗普遍维生素 D 缺乏症这一公共卫生问题。本文通过详细阐述因果关系图，探讨了补充维生素 D 的免疫调节作用。除了 D，还应补充维生素 K 和镁，以预防长期健康风险。需要进行后续的临床随机试验来验证当前的间接证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3563/7406600/421c91f607ba/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3563/7406600/421c91f607ba/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3563/7406600/421c91f607ba/gr1_lrg.jpg

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