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双能 CT 在弥漫性肝病中的应用:是否有作用?

Dual-energy CT in diffuse liver disease: is there a role?

机构信息

Toronto Joint Department of Medical Imaging, University Health Network, Sinai Health System and Women's College Hospital, University of Toronto, Toronto, ON, Canada.

Abdominal Imaging Section, Department of Radiology, University of Washington School of Medicine, Seattle, WA, 98195, USA.

出版信息

Abdom Radiol (NY). 2020 Nov;45(11):3413-3424. doi: 10.1007/s00261-020-02702-4. Epub 2020 Aug 8.

DOI:10.1007/s00261-020-02702-4
PMID:32772121
Abstract

Dual-energy CT (DECT) can be defined as the use of two different energy levels to identify and quantify material composition. Since its inception, DECT has benefited from remarkable improvements in hardware and clinical applications. DECT enables accurate identification and quantification of multiple materials, including fat, iron, and iodine. As a consequence, multiple studies have investigated the potential role of DECT in the assessment of diffuse liver diseases. While this role is evolving, this article aims to review the most relevant literature on use of DECT for assessment of diffuse liver diseases. Moreover, the basic concepts on DECT techniques, types of image reconstruction, and DECT-dedicated software will be described, focusing on the areas that are most relevant for the evaluation of diffuse liver diseases. Also, we will review the evidence of added value of DECT in detection and assessment of hepatocellular carcinoma which is a known risk in patients with diffuse liver disease.

摘要

双能 CT(DECT)可以定义为使用两种不同的能量水平来识别和量化物质成分。自诞生以来,DECT 在硬件和临床应用方面取得了显著的进步。DECT 能够准确识别和量化多种物质,包括脂肪、铁和碘。因此,多项研究探讨了 DECT 在弥漫性肝脏疾病评估中的潜在作用。虽然这一作用仍在不断发展,但本文旨在回顾 DECT 用于评估弥漫性肝脏疾病的相关文献。此外,还将描述 DECT 技术的基本概念、图像重建类型和 DECT 专用软件,重点介绍与评估弥漫性肝脏疾病最相关的领域。还将回顾 DECT 在检测和评估弥漫性肝脏疾病患者已知风险的肝细胞癌中的附加价值证据。

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本文引用的文献

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Assessing Liver Hemodynamics in Children With Cholestatic Cirrhosis by Use of Dual-Energy Spectral CT.应用双能量光谱 CT 评估胆汁淤积性肝硬化患儿的肝脏血流动力学。
AJR Am J Roentgenol. 2020 Mar;214(3):665-670. doi: 10.2214/AJR.19.22035. Epub 2020 Jan 22.
2
Double Low-Dose Dual-Energy Liver CT in Patients at High-Risk of HCC: A Prospective, Randomized, Single-Center Study.双低剂量双能 CT 用于 HCC 高危患者:一项前瞻性、随机、单中心研究。
Invest Radiol. 2020 Jun;55(6):340-348. doi: 10.1097/RLI.0000000000000643.
3
Liver Fat Content Measurement with Quantitative CT Validated against MRI Proton Density Fat Fraction: A Prospective Study of 400 Healthy Volunteers.
双能CT成像的现状与未来:我们能期待什么(以及不能期待什么)?
J Imaging. 2024 Jun 26;10(7):154. doi: 10.3390/jimaging10070154.
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Photon-counting CT: technical features and clinical impact on abdominal imaging.光子计数 CT:腹部成像的技术特点和临床影响。
Abdom Radiol (NY). 2024 Dec;49(12):4383-4399. doi: 10.1007/s00261-024-04414-5. Epub 2024 Jun 18.
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Post-contrast CT liver attenuation alone is superior to the liver-spleen difference for identifying moderate hepatic steatosis.单纯增强 CT 肝脏衰减值对于诊断中度肝脂肪变优于肝脾 CT 值差异。
Eur Radiol. 2024 Nov;34(11):7041-7052. doi: 10.1007/s00330-024-10816-2. Epub 2024 Jun 4.
6
Noninvasive diagnosis of liver cirrhosis: qualitative and quantitative imaging biomarkers.肝硬化的非侵入性诊断:定性和定量成像生物标志物
Abdom Radiol (NY). 2024 Jun;49(6):2098-2115. doi: 10.1007/s00261-024-04225-8. Epub 2024 Feb 19.
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Spectral CT: Current Liver Applications.光谱CT:当前在肝脏方面的应用
Diagnostics (Basel). 2023 May 9;13(10):1673. doi: 10.3390/diagnostics13101673.
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Iodine maps derived from sparse-view kV-switching dual-energy CT equipped with a deep learning reconstruction for diagnosis of hepatocellular carcinoma.基于配备深度学习重建的稀疏视角千伏切换双能 CT 的碘图用于肝细胞癌的诊断。
Sci Rep. 2023 Mar 3;13(1):3603. doi: 10.1038/s41598-023-30460-y.
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Acad Radiol. 2019 Jul;26(7):872-877. doi: 10.1016/j.acra.2018.08.018. Epub 2018 Sep 24.
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Radiology. 2018 Dec;289(3):816-830. doi: 10.1148/radiol.2018181494. Epub 2018 Sep 25.