Department of Psychology, Lund University, Lund, Sweden.
Twin Res Hum Genet. 2020 Aug;23(4):228-234. doi: 10.1017/thg.2020.63. Epub 2020 Aug 10.
The aim of the study was to examine the Family and School Psychosocial Environment (FSPE) questionnaire in relation to a possible genotype-environment correlation and genetic mediation between the FSPE variables and personality variables, assessed by the Junior Eysenck Personality Questionnaire. A sample of 506 Swedish children aged 10-20 years from 253 families were recruited via the Swedish state population and address register and SchoolList.Eu. The children were divided into 253 pairs: 46 monozygotic twin pairs, 42 dizygotic twin pairs, 140 pairs of full siblings and 25 pairs of half-siblings. The behavioral genetic analysis showed that both FSPE factors, Warmth and Conflicts, may be partly influenced by genetic factors (suggesting genotype-environment correlation) and that nonadditive genetic factors may mediate the relationship between FSPE factors and psychoticism/antisocial personality (P). An indication of a special shared monozygotic twin environment was found for P and Lie/social desirability, but based on prior research findings this factor may have a minor influence on P and L. P and L were negatively correlated, and the relationship seems to be partly mediated by nonadditive genetic factors. Nonshared environment and measurement errors seem to be the most influential mediating factors, but none of the cross-twin cross-dimension correlations suggest a common shared environmental mediating factor.
这项研究的目的是探讨家庭和学校心理社会环境（FSPE）问卷与可能的基因型-环境相关性以及 FSPE 变量与人格变量之间的遗传中介之间的关系，人格变量由青少年艾森克人格问卷评估。通过瑞典国家人口和地址登记处以及 SchoolList.Eu，从 253 个家庭中招募了 506 名年龄在 10-20 岁的瑞典儿童作为样本。这些儿童被分为 253 对：46 对同卵双胞胎、42 对异卵双胞胎、140 对全同胞和 25 对半同胞。行为遗传学分析表明，FSPE 的两个因素，温暖和冲突，可能部分受到遗传因素的影响（表明基因型-环境相关性），非加性遗传因素可能介导 FSPE 因素与精神病/反社会人格（P）之间的关系。发现 P 和 Lie/社交期望存在特殊的共享同卵双胞胎环境的迹象，但基于先前的研究结果，该因素对 P 和 L 的影响可能较小。P 和 L 呈负相关，这种关系似乎部分由非加性遗传因素介导。非共享环境和测量误差似乎是最具影响力的中介因素，但双胞胎间跨维度的相关性都没有表明存在共同的共享环境中介因素。
