Mulholland M W, Debas H T
Department of Surgery, University of Washington, Seattle 98195.
Surgery. 1988 Feb;103(2):135-47.
Recent advances in understanding the physiology and pathophysiology of the gastrointestinal hormone, gastrin, are reviewed. Details of gastrin biosynthesis, secretion, and cellular actions may have broad implications for other peptide hormones. Potentially useful antigastrin drugs are described. Areas of future development are suggested.
本文综述了胃肠激素胃泌素在生理学和病理生理学方面的最新研究进展。胃泌素生物合成、分泌及细胞作用的细节可能对其他肽类激素具有广泛影响。文中还描述了具有潜在应用价值的抗胃泌素药物,并提出了未来的发展方向。