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改良经皮经肝胆道球囊扩张术治疗难治性肝胆管结石。

Modified percutaneous transhepatic papillary balloon dilation for patients with refractory hepatolithiasis.

机构信息

Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan 250033, Shandong Province, China.

Department of Cancer Center, The First Affiliated Hospital of Shandong First Medical University, Jinan 250014, Shandong Province, China.

出版信息

World J Gastroenterol. 2020 Jul 21;26(27):3929-3937. doi: 10.3748/wjg.v26.i27.3929.

Abstract

BACKGROUND

Some patients with hepatolithiasis cannot tolerate surgery due to severe cardiac or pulmonary comorbidities, or cannot be endoscopically treated because of altered gastrointestinal anatomies.

AIM

To propose a modified percutaneous transhepatic papillary balloon dilation procedure, and evaluate the clinical efficacy and safety of this modality.

METHODS

Data from 21 consecutive patients who underwent modified percutaneous transhepatic papillary balloon dilation with hepatolithiasis were retrospectively analyzed. Using auxiliary devices, intrahepatic bile duct stones were pushed into the common bile duct and expelled into the duodenum with an inflated balloon catheter. The outcomes recorded included success rate, procedure time, hospital stay, causes of failure, and procedure-related complications. Patients with possible long-term complications were followed up for 2 years.

RESULTS

Intrahepatic bile duct stones were successfully removed in 20 (95.23%) patients. Mean procedure time was 65.8 ± 5.3 min. Mean hospital stay was 10.7 ± 1.5 d. No pancreatitis, gastrointestinal, or biliary duct perforation was observed. All patients were followed up for 2 years, and there was no evidence of reflux cholangitis or calculi recurrence.

CONCLUSION

Modified percutaneous transhepatic papillary balloon dilation was feasible and safe with a small number of patients with hepatolithiasis, and may be a treatment option in patients with severe comorbidities or in patients in whom endoscopic procedure was not successful.

摘要

背景

一些患有肝胆管结石的患者由于严重的心脏或肺部合并症而无法耐受手术,或由于胃肠道解剖结构改变而无法进行内镜治疗。

目的

提出一种改良的经皮经肝胆道球囊扩张术,并评估该方法的临床疗效和安全性。

方法

回顾性分析了 21 例接受改良经皮经肝胆道球囊扩张术治疗肝胆管结石的连续患者的数据。使用辅助装置,将肝内胆管结石推入胆总管,并通过充气球囊导管将其排入十二指肠。记录的结果包括成功率、手术时间、住院时间、失败原因和与手术相关的并发症。对可能有长期并发症的患者进行了 2 年的随访。

结果

20 例(95.23%)患者成功取出肝内胆管结石。平均手术时间为 65.8±5.3 分钟。平均住院时间为 10.7±1.5 天。未观察到胰腺炎、胃肠道或胆管穿孔。所有患者均随访 2 年,无反流性胆管炎或结石复发证据。

结论

改良经皮经肝胆道球囊扩张术对于少数肝胆管结石患者是可行和安全的,可能是严重合并症患者或内镜治疗不成功患者的一种治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/67af/7385557/76292905b37a/WJG-26-3929-g001.jpg

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