Yang Mu, Li Hui, Sun Jiao, Zhao Yi, Tang Dongqi
Institute of Medical Sciences, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, China.
Curr Urol. 2020 Jun;14(2):79-84. doi: 10.1159/000499255. Epub 2020 Jun 23.
Coronavirus disease 2019 (COVID-19) is a new infectious disease that first emerged in December 2019. It has infected more than 4,890,000 people in more than 200 countries. This virus can cause progressive respiratory symptoms and severe diseases such as organ failure and death. The complete genomic sequence of SARS-CoV-2 was determined after the virus's identification, and the sequence analysis showed that SARS-CoV-2 strains are genetically similar to SARS-CoV. Angiotensin converting enzyme II is an entry receptor for SARS-CoV-2, which is highly expressed in the kidney, so some patients had symptoms of kidney damage. Here we reviewed the current progress of COVID-19 and its urogenital manifestations. In this rapidly moving field, this review was comprehensive as of May 30, 2020.
2019冠状病毒病(COVID-19)是一种于2019年12月首次出现的新型传染病。它已在200多个国家感染了超过489万人。这种病毒可引发进行性呼吸道症状以及诸如器官衰竭和死亡等严重疾病。在该病毒被识别后确定了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的完整基因组序列,序列分析表明SARS-CoV-2毒株在基因上与严重急性呼吸综合征冠状病毒(SARS-CoV)相似。血管紧张素转换酶II是SARS-CoV-2的一种进入受体,在肾脏中高度表达,因此一些患者出现了肾损伤症状。在此我们综述了COVID-19的当前进展及其泌尿生殖系统表现。在这个快速发展的领域,本综述截至2020年5月30日是全面的。