Zegmout Adil, Rouihi Ahmed, Boucaid Abdelhalim, Amchich Younes, Souhi Hicham, El Ouazzani Hanane, Rhorfi Ismail Abderrahmane, Abid Ahmed
Service de Pneumologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Service d'ORL, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
Pan Afr Med J. 2020 Jun 12;36:84. doi: 10.11604/pamj.2020.36.84.13067. eCollection 2020.
Primary naso-sinusal tuberculosis (TB) is a relatively rare or exceptional disorder characterized by polymorphic or non-specific clinical manifestation. Diagnosis is based on anatomo-pathological examination and mycobacteriology test of biopsy specimen. Predictor of good outcome is early conventional anti-tuberculous antibiotic therapy. However, our study reports recurrence at this rare site in an immunocompetent patient despite early suitable TB treatment and good adherence with therapy. Relapse was correlated with underdosing of rifampicin. This study highlights the diagnostic, etiological and therapeutic management of this relapse. Our experience could help clinicians to better manage this uncommon condition.
原发性鼻-鼻窦结核是一种相对罕见或特殊的疾病，其临床表现具有多形性或非特异性。诊断基于活检标本的解剖病理学检查和分枝杆菌学检测。良好预后的预测因素是早期进行常规抗结核抗生素治疗。然而，我们的研究报告了一名免疫功能正常的患者在这个罕见部位复发，尽管早期进行了适当的结核病治疗且患者对治疗的依从性良好。复发与利福平剂量不足有关。本研究强调了这种复发情况的诊断、病因和治疗管理。我们的经验有助于临床医生更好地处理这种罕见病症。
