Kinoshita Hideki, Jumonji Mai, Yasuda Shin, Igoshi Keiji
Department of Bioscience, School of Agriculture, Tokai University, 9-1-1 Toroku, Higashi-ku, Kumamoto-shi, Kumamoto, Japan.
Department of Food Management, School of Food, Agricultural and Environmental Sciences, Miyagi University, 2-2-1 Hatatate, Taihaku-ku, Sendai-shi, Miyagi, Japan.
Biosci Microbiota Food Health. 2020;39(3):183-187. doi: 10.12938/bmfh.2019-049. Epub 2020 May 2.
Heavy metals are harmful to human health. Therefore, we investigated the biosorption of heavy metals by lactic acid bacteria (LAB). Of all the tested heavy metals, biosorption by LAB was highest for mercury, followed by lead, cadmium, and finally arsenic. The viability of HCT-116 cells was reduced by half in the presence of 7.5 µg/mL mercury but recovered after the addition of selected LAB strains. HCT-116 cells showed increased superoxide dismutase and catalase activities, whereas glutathione peroxidase activities decreased significantly. Addition of TOKAI 57m recovered all antioxidant enzyme activities. Our results suggest that this strain can be used for cellular detoxification.
重金属对人体健康有害。因此，我们研究了乳酸菌（LAB）对重金属的生物吸附作用。在所有测试的重金属中，LAB对汞的生物吸附作用最高，其次是铅、镉，最后是砷。在存在7.5 µg/mL汞的情况下，HCT-116细胞的活力降低了一半，但在添加选定的LAB菌株后恢复。HCT-116细胞的超氧化物歧化酶和过氧化氢酶活性增加，而谷胱甘肽过氧化物酶活性显著降低。添加TOKAI 57m可恢复所有抗氧化酶活性。我们的结果表明，该菌株可用于细胞解毒。
