An analysis of SARS-CoV-2 cell entry genes identifies the intestine and colorectal cancer as susceptible tissues.
作者信息
Darvish-Damavandi Mahnaz, Laycock James, Ward Christopher, van Driel Milou S, Goldgraben Mae A, Buczacki Simon Ja
机构信息
Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Puddicombe Way, Cambridge, UK.
Cambridge Colorectal Unit, Cambridge University Hospitals NHS Trust, Hills Road, Cambridge, UK.
出版信息
Br J Surg. 2020 Oct;107(11):e452-e454. doi: 10.1002/bjs.11911. Epub 2020 Aug 10.
Abstract
摘要
相似文献
1
An analysis of SARS-CoV-2 cell entry genes identifies the intestine and colorectal cancer as susceptible tissues.对严重急性呼吸综合征冠状病毒2（SARS-CoV-2）细胞进入基因的分析表明，肠道和结直肠癌是易感组织。
Br J Surg. 2020 Oct;107(11):e452-e454. doi: 10.1002/bjs.11911. Epub 2020 Aug 10.
2
Identification of Transcription Factors Regulating SARS-CoV-2 Entry Genes in the Intestine.鉴定调控肠道中新冠病毒（SARS-CoV-2）进入基因的转录因子
Cell Mol Gastroenterol Hepatol. 2021;11(1):181-184. doi: 10.1016/j.jcmgh.2020.08.005. Epub 2020 Aug 15.
3
Increased expression of key SARS-CoV-2 entry points in multiple tissues in individuals with NAFLD.非酒精性脂肪性肝病（NAFLD）患者多种组织中新冠病毒（SARS-CoV-2）关键进入点的表达增加。
J Hepatol. 2021 Mar;74(3):748-749. doi: 10.1016/j.jhep.2020.12.007. Epub 2020 Dec 16.
4
Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin.人胎盘滋养层细胞表达 SARS-CoV-2 进入因子 ACE2、TMPRSS2 和 Furin。
mSphere. 2021 Apr 14;6(2):e00250-21. doi: 10.1128/mSphere.00250-21.
5
Cigarette Smoke Stimulates SARS-CoV-2 Internalization by Activating AhR and Increasing ACE2 Expression in Human Gingival Epithelial Cells.香烟烟雾通过激活 AhR 和增加人牙龈上皮细胞中 ACE2 的表达来刺激 SARS-CoV-2 的内化。
Int J Mol Sci. 2021 Jul 18;22(14):7669. doi: 10.3390/ijms22147669.
6
Comparative analyses of ACE2 and TMPRSS2 gene: Implications for the risk to which vertebrate animals are susceptible to SARS-CoV-2.ACE2 和 TMPRSS2 基因的比较分析：对脊椎动物易感染 SARS-CoV-2 的风险的启示。
J Med Virol. 2021 Sep;93(9):5487-5504. doi: 10.1002/jmv.27073. Epub 2021 May 19.
7
Contributions of human ACE2 and TMPRSS2 in determining host-pathogen interaction of COVID-19.人类血管紧张素转换酶2（ACE2）和跨膜丝氨酸蛋白酶2（TMPRSS2）在决定新型冠状病毒肺炎（COVID-19）宿主-病原体相互作用中的作用。
J Genet. 2021;100(1). doi: 10.1007/s12041-021-01262-w.
8
Classical and alternative receptors for SARS-CoV-2 therapeutic strategy.经典和替代 SARS-CoV-2 治疗策略受体。
Rev Med Virol. 2021 Sep;31(5):1-9. doi: 10.1002/rmv.2207. Epub 2020 Dec 26.
9
Oral Pathology in COVID-19 and SARS-CoV-2 Infection-Molecular Aspects.COVID-19 和 SARS-CoV-2 感染的口腔病理学-分子方面。
Int J Mol Sci. 2022 Jan 27;23(3):1431. doi: 10.3390/ijms23031431.
10
Targeting the viral-entry facilitators of SARS-CoV-2 as a therapeutic strategy in COVID-19.针对 SARS-CoV-2 的病毒进入促进剂作为 COVID-19 的治疗策略。
J Med Virol. 2021 Sep;93(9):5260-5276. doi: 10.1002/jmv.27019. Epub 2021 May 3.
引用本文的文献
1
Increased TRIM31 gene expression is positively correlated with SARS-CoV-2 associated genes TMPRSS2 and TMPRSS4 in gastrointestinal cancers.TRIM31 基因表达的增加与胃肠道癌症中 SARS-CoV-2 相关基因 TMPRSS2 和 TMPRSS4 呈正相关。
Sci Rep. 2022 Aug 15;12(1):11763. doi: 10.1038/s41598-022-15911-2.
2
and Expressions Are Regulated by and Influence the Gastrointestinal Symptoms Caused by SARS-CoV-2.并且表达受……调节并影响由SARS-CoV-2引起的胃肠道症状。 （注：原文中“and”前和“by”后内容缺失，这是按现有内容尽量完整翻译的结果 ）
J Pers Med. 2021 Nov 16;11(11):1212. doi: 10.3390/jpm11111212.
3
Antibody-Based Immunotherapeutic Strategies for COVID-19.针对新型冠状病毒肺炎的基于抗体的免疫治疗策略
Pathogens. 2020 Nov 5;9(11):917. doi: 10.3390/pathogens9110917.
本文引用的文献
1
Implications of gastrointestinal manifestations of COVID-19.新型冠状病毒肺炎胃肠道表现的影响
Lancet Gastroenterol Hepatol. 2020 Jul;5(7):629-630. doi: 10.1016/S2468-1253(20)30132-1. Epub 2020 May 12.
2
SARS-CoV-2 productively infects human gut enterocytes.SARS-CoV-2 能有效地感染人类肠道肠细胞。
Science. 2020 Jul 3;369(6499):50-54. doi: 10.1126/science.abc1669. Epub 2020 May 1.
3
Immediate and long-term impact of the COVID-19 pandemic on delivery of surgical services.COVID-19 大流行对手术服务提供的即时和长期影响。
Br J Surg. 2020 Sep;107(10):1250-1261. doi: 10.1002/bjs.11670. Epub 2020 Apr 30.
4
Prolonged presence of SARS-CoV-2 viral RNA in faecal samples.严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒RNA在粪便样本中的长期存在。
Lancet Gastroenterol Hepatol. 2020 May;5(5):434-435. doi: 10.1016/S2468-1253(20)30083-2. Epub 2020 Mar 20.
5
Detection of SARS-CoV-2 in Different Types of Clinical Specimens.SARS-CoV-2 在不同类型临床标本中的检测。
JAMA. 2020 May 12;323(18):1843-1844. doi: 10.1001/jama.2020.3786.
6
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor.严重急性呼吸综合征冠状病毒 2 型（SARS-CoV-2）进入细胞依赖于 ACE2 和 TMPRSS2，可被一种临床验证的蛋白酶抑制剂所阻断。
Cell. 2020 Apr 16;181(2):271-280.e8. doi: 10.1016/j.cell.2020.02.052. Epub 2020 Mar 5.
Zotero 插件