Department of Surgery, Boston University/Boston Medical Center; Boston University School of Medicine.
Boston University School of Medicine.
J Natl Med Assoc. 2021 Apr;113(2):125-132. doi: 10.1016/j.jnma.2020.07.009. Epub 2020 Aug 7.
There is very limited comprehensive information on disparate outcomes of black and white patients with COVID-19 infection. Reports from cities and states have suggested a discordant impact on black Americans, but no nationwide study has yet been performed. We sought to understand the differential outcomes for black and white Americans infected with COVID-19.
We obtained case-level data from the Centers for Disease Control and Prevention on 76,442 white and 48,338 non-Hispanic Black patients diagnosed with COVID-19, ages 0 to >80+, outlining information on hospitalization, ICU admission, ventilation, and death outcomes. Multivariate Poisson regressions were used to estimate the association of race, treating white as the reference group, controlling for sex, age group, and the presence of comorbidities.
Black patients were generally younger than white, were more often female, and had larger numbers of comorbidities. Compared to white patients with COVID-19, black patients had 1.4 times the risk of hospitalization (RR 1.42, p < 0.001), and almost twice the risk of requiring ICU care (RR 1.68, p < 0.001) or ventilatory support (RR 1.81, p < 0.001) after adjusting for covariates. Black patients saw a 1.36 times increased risk of death (RR 1.36, p < 0.001) compared to white. Disparities between black and white outcomes increased with advanced age.
Despite the initial descriptions of COVID-19 being a disease that affects all individuals, regardless of station, our data demonstrate the differential racial effects in the United States. This current pandemic reinforces the need to assess the unequal effects of crises on disadvantaged populations to promote population health.
关于感染 COVID-19 的黑人和白人患者的不同结局,仅有非常有限的综合信息。来自城市和州的报告表明,新冠疫情对美国黑人的影响存在差异,但尚未进行全国性研究。我们旨在了解感染 COVID-19 的黑人和美国白人的不同结局。
我们从疾病控制与预防中心获取了 76442 名白人患者和 48338 名非西班牙裔黑人患者的病例级数据,这些患者的年龄在 0 岁至 80 岁以上,记录了住院、入住 ICU、通气和死亡结局的信息。使用多变量泊松回归来估计种族的关联,以白人作为参照组,控制性别、年龄组和合并症的存在。
黑人患者通常比白人患者年轻,更多为女性,且合并症的数量更多。与感染 COVID-19 的白人患者相比,黑人患者住院的风险增加 1.4 倍(RR 1.42,p<0.001),需要 ICU 护理(RR 1.68,p<0.001)或通气支持(RR 1.81,p<0.001)的风险几乎增加了一倍,调整了混杂因素后。与白人相比,黑人患者的死亡风险增加了 1.36 倍(RR 1.36,p<0.001)。黑人和白人结局之间的差异随着年龄的增长而增加。
尽管最初描述 COVID-19 是一种影响所有个体的疾病,与地位无关,但我们的数据表明,在美国存在不同种族的影响。这场当前的大流行再次强调,需要评估危机对弱势人群的不平等影响,以促进人口健康。