COVID-19 患者皮肤表现的临床和组织病理学发现。
Clinical and histopathological findings of cutaneous manifestations of COVID-19 patients.
机构信息
Institute of Health Sciences, Department of Nursing, University of International Integration of Afro-Brazilian Lusophony, Ceará, Brazil.
University of São Paulo, Department of Nursing. Sírio Libanês Hospital, São Paulo, Brazil.
出版信息
Dermatol Ther. 2020 Nov;33(6):e13926. doi: 10.1111/dth.13926. Epub 2020 Sep 28.
Coronavirus disease (COVID-19) became pandemic since this is a disease with a high infection rate. The study's object is to identify clinical and histopathological findings of cutaneous manifestations of COVID-19 patients. The evidence was analyzed in PubMed, CINAHL, Cochrane, Web of Science, and Scopus, with the search strategy (covid 19 OR covid-19 OR corona OR coronavirus OR sars-cov-2) AND (cutaneous or cutaneous manifestations OR), and 17 studies were included, involving 351 cases with COVID19 and skin manifestations. The lesions were classified mainly as maculopapular, erythematous, vesicular, and urticarial. Histopathological analyses suggest a predominance of spongiosis, perivascular infiltrate of lymphocytes, and thrombogenic vasculopathy.
冠状病毒病（COVID-19）已成为大流行疾病，因为这是一种具有高感染率的疾病。本研究的目的是确定 COVID-19 患者皮肤表现的临床和组织病理学发现。证据在 PubMed、CINAHL、Cochrane、Web of Science 和 Scopus 中进行了分析，检索策略为（covid 19 或 covid-19 或 corona 或 coronavirus 或 sars-cov-2）和（皮肤或皮肤表现或），纳入了 17 项研究，共涉及 351 例 COVID19 合并皮肤表现的患者。病变主要分类为斑丘疹、红斑、水疱和荨麻疹。组织病理学分析提示海绵状水肿、血管周围淋巴细胞浸润和血栓性血管病变为主。
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