Willemsen M A, Loogman M C M, van Buggenum H, Langenveld J, Wassen M M L H
Zuyderland Medisch Centrum, afd. Obstetrie en Gynaecologie, Heerlen.
Contact: M.A. Willemsen (
Ned Tijdschr Geneeskd. 2020 Aug 5;164:D3830.
While chickenpox is usually a mild and self-limiting disease, life-threatening complications can occur, particularly in risk groups such as pregnant women. In the case reported here, a 34-year-old woman, pregnant with her second child, was exposed to the varicella zoster virus (VZV) during the sixth week of pregnancy. Blood results showed seronegative status for VZV. Despite properly and well-timed administration of immunoglobulins, the patient developed chickenpox two weeks after exposure. Two days after developing symptoms she was admitted to the emergency room with fever and sudden shortness of breath. Radiological examination confirmed bilateral pneumonia, most probably due to VZV. Developing chickenpox during pregnancy is not only potentially dangerous for the unborn baby, but also for the mother. All medical specialists involved should be aware of the risks and consequences of this rare, yet dangerous, timing of chickenpox.
虽然水痘通常是一种轻微的自限性疾病,但可能会出现危及生命的并发症,尤其是在孕妇等风险人群中。在本报告的病例中,一名怀有第二胎的34岁女性在怀孕第6周时接触了水痘带状疱疹病毒(VZV)。血液检查结果显示VZV血清学阴性。尽管及时正确地注射了免疫球蛋白,但患者在接触病毒两周后仍患上了水痘。出现症状两天后,她因发热和突然气短被送往急诊室。影像学检查证实为双侧肺炎,很可能是由VZV引起的。怀孕期间感染水痘不仅对未出生的婴儿有潜在危险,对母亲也有危险。所有相关的医学专家都应该意识到这种水痘发病时间罕见但危险的情况所带来的风险和后果。