Tang Yonghua, Xiong Xueqing, Xu Chengjie, Yu Deshuai, Huang Yanyan, Lin Changxu, Liu Xiangyang, Lin Youhui
Research Institute for Biomimetics and Soft Matter, Department of Physics, Fujian Provincial Key Laboratory for Soft Functional Materials Research, Jiujiang Research Institute, Xiamen University, Xiamen, 361005, China.
College of Light Industry and Food Engineering, Nanjing Forestry University, Nanjing, 210037, China.
Nanoscale Res Lett. 2020 Aug 11;15(1):162. doi: 10.1186/s11671-020-03388-9.
Light-activated nanozymes can provide a wealth of new opportunities for the chemical industry and biotechnology. However, present remote-controlled catalytic systems are still far from satisfactory. Herein, we present an interesting example of applying ultrathin Pd nanosheets (Pd NSs) as a light-controllable peroxidase mimic. Since most of Pd atoms are exposed on their surface, Pd NSs with a thickness of 1.1 nm possess high peroxidase-like activity. More importantly, under light excitation, such intrinsic activity can be further activated by a nearly 2.4- to 3.2-fold. Such a phenomenon can be ascribed to the unique optical property of ultrathin Pd NSs, which can efficiently capture photons to generate hot electrons via surface plasmon resonance effect and thus promote the in situ decomposition of HO into reactive oxygen species radicals (O*). This enhanced catalysis can also be used for real-time and highly sensitive colorimetric detection of H2O2. We expect our work can provide valuable insights into the rational design of artificial nanozymes with controllable and efficient activity in biomedical diagnostics, drug delivery, and environmental chemistry.
光激活纳米酶可为化学工业和生物技术提供大量新机遇。然而，目前的远程控制催化系统仍远不能令人满意。在此，我们展示了一个有趣的例子，即应用超薄钯纳米片（Pd NSs）作为光控过氧化物酶模拟物。由于大多数钯原子暴露在其表面，厚度为1.1纳米的Pd NSs具有高类过氧化物酶活性。更重要的是，在光激发下，这种固有活性可被进一步激活近2.4至3.2倍。这种现象可归因于超薄Pd NSs的独特光学性质，其可通过表面等离子体共振效应有效捕获光子以产生热电子，从而促进过氧化氢原位分解为活性氧自由基（O*）。这种增强的催化作用还可用于过氧化氢的实时高灵敏度比色检测。我们期望我们的工作能够为人工纳米酶的合理设计提供有价值的见解，这些纳米酶在生物医学诊断、药物递送和环境化学中具有可控且高效的活性。
