Stray-Pedersen B, Lorentzen-Styr A M
Am J Obstet Gynecol. 1977 Aug 1;128(7):716-21. doi: 10.1016/0002-9378(77)90709-8.
Serologic testing for Toxoplasma antibodies (dye test, indirect fluorescent antibody test on serum, and complement-fixation test) was done in 96 women with habitual abortions and 61 women with sporadic abortions. In 61 of these women, endometrial biopsies were examined for content of T. gondii (animal inoculation procedures, immunofluorescence microscopy). Control subjects were 59 women with no spontaneous abortions. In seven patients (one control patient and six with habitual abortion), tachyzoites of T. gondii were observed in repeated biopsies from the endometrium and in menstrual blood by the immunofluorescence method. In no case, however, could T. gondii be isolated from the endometrium by inoculations. Moreover, the serologic results obtained among the patients with habitual abortion did not differ significantly from those obtained among the ones with sporadic abortion or among the control subjects. Five of the women with Toxoplasma-positive endometrium were serologically negative. Treatment of the Toxoplasma-positive women with antitoxoplasma drugs led to removal of parasites from the endometrium. T. gondii was not observed in the semen of the husbands.
对96例习惯性流产妇女和61例偶发性流产妇女进行了弓形虫抗体血清学检测（染色试验、血清间接荧光抗体试验和补体结合试验）。其中61例妇女进行了子宫内膜活检，以检查弓形虫的含量（动物接种程序、免疫荧光显微镜检查）。对照组为59例无自然流产的妇女。通过免疫荧光法，在7例患者（1例对照患者和6例习惯性流产患者）的子宫内膜重复活检组织和月经血中观察到了弓形虫速殖子。然而，通过接种均未从子宫内膜中分离出弓形虫。此外，习惯性流产患者的血清学结果与偶发性流产患者或对照组的结果无显著差异。5例子宫内膜弓形虫阳性的妇女血清学检测呈阴性。用抗弓形虫药物治疗弓形虫阳性妇女可使子宫内膜中的寄生虫清除。在其丈夫的精液中未观察到弓形虫。
