Adefisan A S, Olagbuji B N, Adeniyi A A, Ade-Ojo I P, Ghazalli S M, Olofinbiyi B A
Department of Obstetrics and Gynaecology, Ekiti State University Teaching Hospital, Ado Ekiti, Ekiti State, Nigeria.
Department of Obstetrics and Gynaecology, Federal Teaching Hospital, Ido Ekiti, Ekiti State, Nigeria.
Niger J Clin Pract. 2020 Aug;23(8):1087-1094. doi: 10.4103/njcp.njcp_221_19.
Maternal hyperglycemia first diagnosed in pregnancy, previously referred to as gestational diabetes mellitus is associated with health consequences for both the mother and her fetus/baby, not only in the short term but also in the long term. Early screening helps to identify women with overt diabetes or those with early onset GDM.
The aim of this study was to determine the diagnostic performance of two screening tests (Random plasma glucose, Random capillary glucose) in relation to 75g Oral glucose tolerance test (OGTT) done before 24 weeks gestation.
This prospective longitudinal cohort study was carried out between 1 February, 2017 and 31 July, 2017, at two teaching hospitals in Nigeria. Two hundred and eighty one (281) pregnant women who met the inclusion criteria were selected and screened with both random plasma glucose (RPG) and random capillary glucose (RCG) before 24 weeks of pregnancy. They were then made to undergo 75g OGTT a week later. The diagnostic performance of the screening tests were determined.
A total of 270 women had 75g OG.
Random plasma glucose and Random capillary glucose performed poorly compared to 75g-OGTT in detecting hyperglycemia in early pregnancy.
孕期首次诊断出的母体高血糖，以前称为妊娠期糖尿病，对母亲及其胎儿/婴儿的健康都会产生影响，不仅在短期内如此，长期来看也是如此。早期筛查有助于识别患有显性糖尿病或早发型妊娠期糖尿病的女性。
本研究的目的是确定两种筛查试验（随机血糖、随机毛细血管血糖）相对于妊娠24周前进行的75克口服葡萄糖耐量试验（OGTT）的诊断效能。
这项前瞻性纵向队列研究于2017年2月1日至2017年7月31日在尼日利亚的两家教学医院进行。选择了281名符合纳入标准的孕妇，在妊娠24周前用随机血糖（RPG）和随机毛细血管血糖（RCG）进行筛查。然后让她们在一周后进行75克OGTT。确定筛查试验的诊断效能。
共有270名女性进行了75克OG。
在检测妊娠早期高血糖方面，与75克OGTT相比，随机血糖和随机毛细血管血糖的表现较差。
