三级医院新生儿败血症的微红细胞沉降率：描述性横断面研究。

Micro-Erythrocyte Sedimentation Rate in Neonatal Sepsis of a Tertiary Hospital: A Descriptive Cross-sectional Study.

机构信息

Neonatal Unit, Department of Paediatrics, Kathmandu Medical College and Teaching Hospital, Sinamangal, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2020 Jun 30;58(226):377-382. doi: 10.31729/jnma.4984.

DOI:10.31729/jnma.4984

PMID:32788752

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7580353/

Abstract

INTRODUCTION

Neonatal sepsis is the most important cause of morbidity and mortality among low birth weight and preterm babies in developing countries. The main objective of this study is to find the level of micro-Erythrocyte sedimentation rate in neonatal sepsis.

METHODS

This is a descriptive cross-sectional study conducted at the neonatal unit over six months period (November 2019 to April 2020). All preterm, term and post-term babies with neonatal sepsisdelivered at Kathmandu Medical College Teaching Hospital were enrolled. Ethical clearance was received from the Institutional Review Committee of Kathmandu Medical College (Ref: 181020191). Convenient sampling method was applied and statistical analysis was done with Statistical package for social sciences 19 version.

RESULTS

Out of 75 babies, confirm sepsis is 13 (17.3%), probable sepsis is 40 (53.4%) and suspected sepsis is 22 (29.2%). Micro-Erythrocyte sedimentation level is elevated (≥15mm in 1st hr) in 25 (33.3%) babies with a mean micro-Erythrocyte sedimentation level 9.32±5.4 (2-18) mm in 1st hr. The elevated micro- Erythrocyte sedimentation level was seen in relation to sepsis types and C-reactive protein.

CONCLUSIONS

The bedside micro-Erythrocyte sedimentation level aids in the diagnosis of neonatal sepsis.

摘要

简介

新生儿败血症是发展中国家低出生体重儿和早产儿发病率和死亡率的主要原因。本研究的主要目的是寻找新生儿败血症的微红细胞沉降率水平。

方法

这是一项在六个月期间（2019 年 11 月至 2020 年 4 月）在新生儿病房进行的描述性横断面研究。在加德满都医学院教学医院分娩的所有早产儿、足月儿和过期产儿中，患有新生儿败血症的均被纳入研究。本研究已获得加德满都医学院机构审查委员会的伦理批准（注册号：181020191）。采用便利抽样法，使用社会科学统计软件 19 版进行统计分析。

结果

在 75 名婴儿中，确诊败血症 13 例（17.3%），疑似败血症 40 例（53.4%），可疑败血症 22 例（29.2%）。25 例（33.3%）婴儿的微红细胞沉降率升高（第 1 小时≥15mm），第 1 小时的平均微红细胞沉降率为 9.32±5.4（2-18）mm。升高的微红细胞沉降率与败血症类型和 C 反应蛋白有关。