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肋骨软骨肉瘤

Chondrosarcoma of the Ribs.

作者信息

Tahir Muhammad, Rahman Jawaria, Arekemase Hassan, Zubair Tayyaba, Basit Abdul

机构信息

Pathology, Case Western Reserve University School of Medicine, Cleveland, USA.

Pathology, City of Hope, Comprehensive Cancer Center, Monrovia, USA.

出版信息

Cureus. 2020 Jul 12;12(7):e9158. doi: 10.7759/cureus.9158.

DOI:10.7759/cureus.9158
PMID:32789094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7417322/
Abstract

Chondrosarcoma is a unique kind of tumor that originates from the cartilage-producing neoplastic mesenchymal cells and appears in both the appendicular and atlantoaxial skeleton. It is the second most prevalent neoplastic bone tumor, with an occurrence of 0.79/100,000/year. The biological presentation of this cancer fluctuates extensively, depending on the grade and anatomical location. Since chondrosarcoma is predominantly resistant to conventional chemo- and radiation therapy, surgical resection remains the sole curative treatment, although at present new treatment modalities are under investigation.

摘要

软骨肉瘤是一种独特的肿瘤,起源于产生软骨的肿瘤性间充质细胞,可出现在四肢骨骼和寰枢椎骨骼中。它是第二常见的原发性骨肿瘤,年发病率为0.79/10万。这种癌症的生物学表现差异很大,取决于分级和解剖位置。由于软骨肉瘤主要对传统的化疗和放疗耐药,手术切除仍然是唯一的治愈性治疗方法,尽管目前正在研究新的治疗方式。

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Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma.高级骨肉瘤和软骨肉瘤的治疗靶点和新型治疗选择的最新进展。
Hematol Oncol Clin North Am. 2013 Oct;27(5):1021-48. doi: 10.1016/j.hoc.2013.07.012. Epub 2013 Aug 26.
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Update on chondrosarcomas.软骨肉瘤的最新进展
Curr Opin Oncol. 2007 Jul;19(4):371-6. doi: 10.1097/CCO.0b013e32812143d9.
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Staging of primary malignancies of bone.原发性骨恶性肿瘤的分期
Cureus. 2024 Apr 4;16(4):e57594. doi: 10.7759/cureus.57594. eCollection 2024 Apr.
4
Primary Chondrosarcoma of the Right Fourth Rib Resected at the Marginal Margin: A Case Report.右侧第四肋骨边缘切除的原发性软骨肉瘤:一例报告
Cureus. 2023 Dec 28;15(12):e51251. doi: 10.7759/cureus.51251. eCollection 2023 Dec.
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Malignant chest wall neoplasms of bone and cartilage: a pictorial review of CT and MR findings.骨与软骨恶性胸壁肿瘤:CT与MR表现的影像综述
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Emerging pathways in the development of chondrosarcoma of bone and implications for targeted treatment.骨软骨肉瘤发展中的新途径及其对靶向治疗的意义。
Lancet Oncol. 2005 Aug;6(8):599-607. doi: 10.1016/S1470-2045(05)70282-5.
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Synchronous development of breast cancer and chest wall fibrosarcoma after previous mantle radiation for Hodgkin's disease.既往因霍奇金病接受斗篷野放疗后同步发生乳腺癌和胸壁纤维肉瘤
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Chest wall tumors: radiologic findings and pathologic correlation: part 2. Malignant tumors.胸壁肿瘤:影像学表现与病理对照:第2部分。恶性肿瘤。
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