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肋骨软骨肉瘤

Chondrosarcoma of the Ribs.

作者信息

Tahir Muhammad, Rahman Jawaria, Arekemase Hassan, Zubair Tayyaba, Basit Abdul

机构信息

Pathology, Case Western Reserve University School of Medicine, Cleveland, USA.

Pathology, City of Hope, Comprehensive Cancer Center, Monrovia, USA.

出版信息

Cureus. 2020 Jul 12;12(7):e9158. doi: 10.7759/cureus.9158.

Abstract

Chondrosarcoma is a unique kind of tumor that originates from the cartilage-producing neoplastic mesenchymal cells and appears in both the appendicular and atlantoaxial skeleton. It is the second most prevalent neoplastic bone tumor, with an occurrence of 0.79/100,000/year. The biological presentation of this cancer fluctuates extensively, depending on the grade and anatomical location. Since chondrosarcoma is predominantly resistant to conventional chemo- and radiation therapy, surgical resection remains the sole curative treatment, although at present new treatment modalities are under investigation.

摘要

软骨肉瘤是一种独特的肿瘤,起源于产生软骨的肿瘤性间充质细胞,可出现在四肢骨骼和寰枢椎骨骼中。它是第二常见的原发性骨肿瘤,年发病率为0.79/10万。这种癌症的生物学表现差异很大,取决于分级和解剖位置。由于软骨肉瘤主要对传统的化疗和放疗耐药,手术切除仍然是唯一的治愈性治疗方法,尽管目前正在研究新的治疗方式。

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