高级骨肉瘤和软骨肉瘤的治疗靶点和新型治疗选择的最新进展。
Update on targets and novel treatment options for high-grade osteosarcoma and chondrosarcoma.
机构信息
Department of Pathology, Leiden University Medical Center, PO Box 9600, L1-Q, Leiden RC 2300, The Netherlands.
出版信息
Hematol Oncol Clin North Am. 2013 Oct;27(5):1021-48. doi: 10.1016/j.hoc.2013.07.012. Epub 2013 Aug 26.
PMID:24093174
Abstract
Osteosarcoma and chondrosarcoma are the 2 most common malignant bone tumors. This review discusses the clinicopathologic features, recent preclinical developments, and targets currently being or to be validated in the clinic.
摘要
骨肉瘤和软骨肉瘤是 2 种最常见的恶性骨肿瘤。本综述讨论了其临床病理特征、近期临床前研究进展，以及当前正在或即将在临床中验证的靶点。
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