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评估因饮用咖啡浸提液而接触镉和铅的风险。

Assessment of the risk of exposure to cadmium and lead as a result of the consumption of coffee infusions.

机构信息

Department of Bromatology and Food Physiology, University of Life Sciences in Lublin, Akademicka 13, 20-950, Lublin, Poland.

State Scientific-Research Control Institute of Veterinary Medical Products and Feed Additives, Lviv, Ukraine.

出版信息

Biol Trace Elem Res. 2021 Jun;199(6):2420-2428. doi: 10.1007/s12011-020-02332-3. Epub 2020 Aug 13.

DOI:10.1007/s12011-020-02332-3
PMID:32789644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8055627/
Abstract

The paper aimed to analyse the safety of drinking coffee by adult Poles in terms of Pb and Cd content. The degree to which Cd and Pb passed from coffee grounds into the coffee infusion was also examined. Twenty-three samples of natural coffee were examined. The content of metals was determined using the ICP method. On average, dry coffee contained ca. 0.004 μg Cd and 0.05 μg Pb per 1 g, and 95.5% Cd and 94% Pb passed into the infusion. Drinking coffee supplies these metals in the amount of less than 2% TWI (tolerable weekly intake) for Cd and BMDL (benchmark dose lower confidence limit) for Pb. In the presented studies, the values of CDI (chronic daily intake), THQ (target hazard quotient) and HI (hazard index) indicators were lower than 1, which means that the risk of developing diseases connected with chronic exposure to Cd and Pb consumed with coffee must be evaluated as very low. The content of Cd and Pb in the analysed coffee infusions was very low, so drinking coffee does not pose a risk for consumers in terms of the content of these metals. However, it must be remembered that no threshold limits for toxic metal consumption exist because these metals accumulate in the body for a long time. The studies presented here also showed a low (r = 0.26) but still a positive correlation between the content of Pb in coffee and the degree (%) to which Pb passed into the infusion. This problem should be thoroughly investigated.

摘要

本文旨在分析波兰成年人喝咖啡的安全性,从 Pb 和 Cd 含量的角度来看。还检查了 Cd 和 Pb 从咖啡渣转移到咖啡浸出物中的程度。检查了 23 份天然咖啡样品。使用 ICP 法测定金属含量。平均而言,干咖啡每 1 克含有约 0.004μg Cd 和 0.05μg Pb,95.5%的 Cd 和 94%的 Pb 转移到浸出液中。喝咖啡摄入的这些金属量低于 Cd 的 TWI(可耐受每周摄入量)和 Pb 的 BMDL(基准剂量置信下限)的 2%。在所进行的研究中,CDI(慢性每日摄入量)、THQ(目标危害系数)和 HI(危害指数)指标的值均低于 1,这意味着必须评估与慢性暴露于 Cd 和 Pb 相关的疾病风险,这些风险与喝咖啡有关,必须评估为非常低。分析的咖啡浸出物中 Cd 和 Pb 的含量非常低,因此从这些金属的含量来看,喝咖啡对消费者没有风险。然而,必须记住,由于这些金属在体内长期积累,不存在有毒金属消费的阈值限制。这里呈现的研究还显示,咖啡中 Pb 的含量与 Pb 转移到浸出液中的程度(%)之间存在低度(r = 0.26)但仍然是正相关。这个问题应该彻底调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bccd/8055627/cae76b2f970d/12011_2020_2332_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bccd/8055627/cae76b2f970d/12011_2020_2332_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bccd/8055627/cae76b2f970d/12011_2020_2332_Fig1_HTML.jpg

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