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Dataset of antigenic distance measures, hemagglutination inhibition, viral lung titers, and weight loss in mice and ferrets when exposed to HA-based vaccination or sub-lethal A(H1) influenza infection.

作者信息

Skarlupka Amanda L, Handel Andreas, Ross Ted M

机构信息

Center for Vaccines and Immunology, University of Georgia, United States.

Department of Epidemiology and Biostatistics, and Health Informatics Institute and Center for the Ecology of Infectious Diseases, University of Georgia, United States.

出版信息

Data Brief. 2020 Aug 2;32:106118. doi: 10.1016/j.dib.2020.106118. eCollection 2020 Oct.

DOI:10.1016/j.dib.2020.106118
PMID:32793786
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7412860/
Abstract
摘要

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1
Dataset of antigenic distance measures, hemagglutination inhibition, viral lung titers, and weight loss in mice and ferrets when exposed to HA-based vaccination or sub-lethal A(H1) influenza infection.当小鼠和雪貂暴露于基于血凝素的疫苗接种或亚致死性A(H1)流感感染时,抗原距离测量、血凝抑制、病毒肺滴度和体重减轻的数据集。
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Computationally optimized broadly reactive vaccine based upon swine H1N1 influenza hemagglutinin sequences protects against both swine and human isolated viruses.基于猪 H1N1 流感血凝素序列的计算优化广谱反应性疫苗可预防猪源性和人源性分离病毒。
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针对H1N1流感病毒的计算优化广谱反应性血凝素疫苗的设计与特性分析
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