Nelson C G, Apisarnthanarax P, Bean S F, Mullins J F
Arch Dermatol. 1977 Jul;113(7):942-5.
Immunofluorescent techniques were used in the study of tissue from a patient with pemphigus vegetans of Hallopeau. The findings were typical of pemphigus, confirming the propriety of classifying this entity as a benign variant of pemphigus, rather than a disease of purely microbial etiology. The question is raised whether other types of vegetating pyodermas actually are separate diseases or represent a spectrum of pemphigus with the clinical appearance dependent on the patient's immunity to his disease. Immunofluorescent studies are proposed as a basis for classification.
免疫荧光技术被用于对一位患有Hallopeau增殖性天疱疮患者的组织进行研究。研究结果具有典型的天疱疮特征,证实了将该病症归类为天疱疮的良性变体而非纯粹由微生物病因引起的疾病的合理性。由此引发了一个问题,即其他类型的增殖性脓疱病究竟是独立的疾病,还是代表了天疱疮的一个谱系,其临床表现取决于患者对自身疾病的免疫力。建议将免疫荧光研究作为分类的依据。