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[Hallopeau型增殖性天疱疮。直接和间接免疫荧光法检测天疱疮抗体]

[Pemphigus vegetans of the Hallopeau type. Detection of pemphigus antibodies with direct and indirect immunofluorescence].

作者信息

Gerharz M, Stadler R

机构信息

Universitäts-Hautklinik und Poliklinik, Klinikum Steglitz der Freien Universität Berlin.

出版信息

Hautarzt. 1987 Jun;38(6):371-4.

PMID:3308773
Abstract

We report the case of a 25-year-old woman with bullous lesions diagnosed as the rare pustular type of pemphigus described by Hallopeau. Direct immunofluorescence studies revealed deposits of IgG and C3 in the intercellular spaces of the epidermis; the indirect immunofluorescence technique revealed circulating antiepithelial IgG antibodies. The skin lesions cleared completely following treatment with systemic corticosteroids and azathioprine. These findings indicate the disease first described by Hallopeau as "pyodermite végétante" does indeed belong to the pemphigus group, being a rare type of pemphigus vegetans.

摘要

我们报告了一例25岁患有大疱性皮损的女性病例,其被诊断为哈洛佩描述的罕见脓疱型天疱疮。直接免疫荧光研究显示,IgG和C3沉积于表皮细胞间隙;间接免疫荧光技术显示循环抗上皮IgG抗体。经全身用皮质类固醇和硫唑嘌呤治疗后,皮肤损害完全消退。这些发现表明,最初被哈洛佩称为“增殖性脓皮病”的疾病确实属于天疱疮组,是一种罕见的增殖性天疱疮类型。

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