非天然氨基酸在合成生物安全性和翻译后修饰研究中的应用。
Noncanonical Amino Acids in Synthetic Biosafety and Post-translational Modification Studies.
机构信息
Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Korea.
Department of Chemistry, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon, 341418, Korea.
出版信息
Chembiochem. 2021 Feb 2;22(3):460-468. doi: 10.1002/cbic.202000437. Epub 2020 Sep 30.
The incorporation of noncanonical amino acids (ncAAs) has been extensively studied because of its broad applicability. In the past decades, various in vitro and in vivo ncAA incorporation approaches have been developed to generate synthetic recombinant proteins. Herein, we discuss the methodologies for ncAA incorporation, and their use in diverse research areas, such as in synthetic biosafety and for studies of post-translational modifications.
非天然氨基酸（ncAAs）的掺入因其广泛的适用性而得到了广泛的研究。在过去的几十年中，已经开发出了各种体外和体内 ncAA 掺入方法来产生合成重组蛋白。本文讨论了 ncAA 掺入的方法及其在不同研究领域的应用，如合成生物安全性和翻译后修饰研究。
Zotero 插件