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风湿性多肌痛。泼尼松龙治疗的突然停药和逐渐停药,临床及实验室观察

Polymyalgia rheumatica. Abrupt and gradual withdrawal of prednisolone treatment, clinical and laboratory observations.

作者信息

Esselinckx W, Doherty S M, Dixon A S

出版信息

Ann Rheum Dis. 1977 Jun;36(3):219-24. doi: 10.1136/ard.36.3.219.

Abstract

Eighteen patients with polymyalgia rheumatica had corticosteroid treatment withdrawn abruptly under close observation. In each case polymyalgic symptoms reappeared but were controlled rapidly when prednisolone was reintroduced. Prednisolone withdrawal was then started by slow decrements of dose. In no patient was it possible to withdraw prednisolone treatment, after using either method, during the period of observation.

摘要

18例风湿性多肌痛患者在密切观察下突然停用皮质类固醇治疗。每例患者的多肌痛症状均再次出现,但重新使用泼尼松龙后症状迅速得到控制。随后开始缓慢减量泼尼松龙剂量。在观察期内,无论采用哪种方法,均无法使任何患者停用泼尼松龙治疗。

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本文引用的文献

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GIANT-CELL MYOCARDITIS WITH MULTIPLE ORGAN INVOLVEMENT.伴有多器官受累的巨细胞性心肌炎
Arch Intern Med. 1965 Sep;116:444-7. doi: 10.1001/archinte.1965.03870030124022.
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Prognosis in the anarthritic rheumatoid syndrome.非关节炎型类风湿综合征的预后
Br Med J. 1963 Feb 23;1(5329):513-8. doi: 10.1136/bmj.1.5329.513.
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Symptomatology resulting from withdrawal of steroid hormone therapy.类固醇激素治疗停药引起的症状学
Arthritis Rheum. 1959 Aug;2:299-321. doi: 10.1002/1529-0131(195908)2:4<299::aid-art1780020403>3.0.co;2-t.
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Giant-cell arteritis, or arteritis of the aged.巨细胞动脉炎,即老年动脉炎。
Br Med J. 1960 Nov 26;2(5212):1562-7. doi: 10.1136/bmj.2.5212.1562.
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Giant-cell (temporal) arteritis.巨细胞(颞)动脉炎
J Pathol Bacteriol. 1954 Apr;67(2):507-19. doi: 10.1002/path.1700670224.

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