Urano Akira, Kasai Hajime, Murai Yushi, Ikeda Hideki, Urushibara Takashi
Department of Respiratory Medicine, Kimitsu Chuo Hospital, Kisarazu, Chiba, Japan.
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba City, Chiba, Japan.
Am J Case Rep. 2020 Aug 14;21:e924476. doi: 10.12659/AJCR.924476.
BACKGROUND The effect of corticosteroids in the management of patients with coronavirus disease 2019 (COVID-19) is unclear. CASE REPORT A 67-year-old man who tested positive for COVID-19 by reverse-transcription PCR (RT-PCR) analysis was admitted to our hospital. On admission, he had no dyspnea and his oxygen saturation (SpO₂) level was normal. Chest imaging revealed ground-glass opacities (GGO) distributed in both lung fields. Four days after admission, bilateral lung shadows worsened, with a slight reduction in SpO₂ levels. Short-term corticosteroid therapy was initiated, and SpO₂ and radiographic findings promptly improved without use of antiviral agents. CONCLUSIONS More data are required to ascertain the role of corticosteroids in the management of COVID-19 pneumonia.
背景 皮质类固醇在2019冠状病毒病(COVID-19)患者管理中的作用尚不清楚。病例报告 一名经逆转录聚合酶链反应(RT-PCR)分析确诊为COVID-19阳性的67岁男性入住我院。入院时,他没有呼吸困难,血氧饱和度(SpO₂)水平正常。胸部影像学检查显示双肺野均有磨玻璃影(GGO)。入院4天后,双侧肺部阴影加重,SpO₂水平略有下降。开始短期皮质类固醇治疗,未使用抗病毒药物,SpO₂和影像学表现迅速改善。结论 需要更多数据来确定皮质类固醇在COVID-19肺炎管理中的作用。