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坏死性大疱性丹毒

Necrotic bullous erysipelas.

作者信息

Agnholt J, Andersen I, Søndergaard G

机构信息

Department of Internal Medicine C, Aalborg Hospital, Denmark.

出版信息

Acta Med Scand. 1988;223(2):191-2. doi: 10.1111/j.0954-6820.1988.tb15786.x.

DOI:10.1111/j.0954-6820.1988.tb15786.x
PMID:3279727
Abstract

During the last few years streptococcal infections have been reported in connection with various cutaneous manifestations with severe or fatal outcome. A 62-year-old female with chronic interstitial nephritis was admitted with progression of confluent bullous lesions on her right leg. She had contracted a superficial scratch on her right foot 2 days prior to admission. Within 16 hours she deteriorated rapidly with symptoms on sepsis. Blood cultures and cutaneous swabs disclosed growth of beta-haemolytic streptococci group A. In spite of correct penicillin treatment she died 28 hours after admission. Skin biopsies from her right leg showed severe necrosis. This report is a reminder that new, cutaneous manifestations of streptococcal disease are still emerging.

摘要

在过去几年中,有报告称链球菌感染与各种皮肤表现相关,可导致严重或致命后果。一名62岁患有慢性间质性肾炎的女性因右腿融合性大疱性病变进展而入院。入院前两天,她右脚出现了一处表浅擦伤。入院后16小时内,她迅速恶化,出现败血症症状。血培养和皮肤拭子培养显示A组β溶血性链球菌生长。尽管进行了正确的青霉素治疗,但她在入院28小时后死亡。她右腿的皮肤活检显示严重坏死。本报告提醒人们,链球菌疾病新的皮肤表现仍在不断出现。

相似文献

1
Necrotic bullous erysipelas.坏死性大疱性丹毒
Acta Med Scand. 1988;223(2):191-2. doi: 10.1111/j.0954-6820.1988.tb15786.x.
2
Bullous erysipelas: clinical presentation, staphylococcal involvement and methicillin resistance.大疱性丹毒:临床表现、葡萄球菌感染及耐甲氧西林情况
Dermatology. 2006;212(1):31-5. doi: 10.1159/000089019.
3
Erysipelas caused by group A streptococcus activates the contact system and induces the release of heparin-binding protein.A 组链球菌引起的丹毒激活了接触系统,并诱导肝素结合蛋白的释放。
J Invest Dermatol. 2010 May;130(5):1365-72. doi: 10.1038/jid.2009.437. Epub 2010 Jan 28.
4
[Clinical manifestations caused by group A streptococci].[A组链球菌引起的临床表现]
Tidsskr Nor Laegeforen. 1990 Aug 30;110(20):2629-33.
5
Streptococcal cause of erysipelas and cellulitis in adults. A microbiologic study using a direct immunofluorescence technique.成人丹毒和蜂窝织炎的链球菌病因。一项采用直接免疫荧光技术的微生物学研究。
Arch Dermatol. 1989 Jun;125(6):779-82.
6
[Toxic-shock-like-syndrome caused by beta-hemolysing group G streptococci in a multimorbid patient with erysipelas].[一名患有丹毒的多病患者中由β-溶血性G组链球菌引起的中毒性休克样综合征]
Dtsch Med Wochenschr. 2006 Feb 10;131(6):263-6. doi: 10.1055/s-2006-924959.
7
Erysipelas and acute myocarditis: an unusual combination.丹毒和急性心肌炎:一种不常见的组合。
Can J Cardiol. 2013 Sep;29(9):1138.e3-5. doi: 10.1016/j.cjca.2012.12.021. Epub 2013 Mar 13.
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[Fulminant streptococcal gangrene of the lower limbs].[下肢暴发性链球菌坏疽]
Ann Cardiol Angeiol (Paris). 1985 Jul-Sep;34(7):493-4.
9
Erysipelas, a large retrospective study of aetiology and clinical presentation.丹毒:一项关于病因和临床表现的大型回顾性研究
BMC Infect Dis. 2015 Sep 30;15:402. doi: 10.1186/s12879-015-1134-2.
10
Recurrent erysipelas of the face with hyperimmune reaction to group C streptococcus.面部复发性丹毒伴对C组链球菌的超敏反应
Br J Dermatol. 2018 Aug;179(2):524-525. doi: 10.1111/bjd.16538. Epub 2018 May 29.

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Rapidly fatal necrotising fasciitis caused by Streptococcus pyogenes.由化脓性链球菌引起的快速致死性坏死性筋膜炎。
J Clin Pathol. 1993 Jul;46(7):617-20. doi: 10.1136/jcp.46.7.617.