Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Open University, Via di Val Cannuta, 247, 00166, Rome, Italy.
Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy.
Acta Diabetol. 2021 Jan;58(1):25-32. doi: 10.1007/s00592-020-01588-4. Epub 2020 Aug 14.
To describe cross-sectional associations of BMI-adjusted handgrip strength with the presence of diabetes and hypertension in a community setting.
Between 2016 and 2018, 601 consecutive elderly active women (70.7 ± 6.9 years) were enrolled. Nutritional status was evaluated by the Mini Nutritional Assessment (MNA) score. Muscle strength and level of fitness were assessed by standardized physical functional tests and handgrip strength (HGS). The majority of participants were overweight or obese (80% with BMI > 25). Prevalence of diabetes and hypertension was 13 and 60%, respectively. Participants in the lowest quartile of BMI-adjusted HGS (RHGS) had significantly higher prevalence of diabetes and hypertension compared with those in the top quartile (20.7 vs 5.3% and 49.3 vs 39.3%, respectively, p < 0.01 for both), without significant differences in nutritional status. Association with the presence of diabetes was significantly weaker in women with higher vs lower RHGS values (OR 0.77; 0.59-0.86 CI95%; p = 0.002), independent of age, abdominal adiposity, and presence of hypertension. RHGS was positively correlated with most of the physical functional tests performed.
RHGS is an easy-to-obtain measure of muscular strength, independently associated with the presence of diabetes in overweight active elderly women. Prospective studies are required to assess its predictive value to identify adults at risk of developing diabetes.
描述在社区环境中，BMI 调整后的握力与糖尿病和高血压的存在之间的横断面关联。
在 2016 年至 2018 年间，纳入了 601 名连续的老年活跃女性（70.7±6.9 岁）。营养状况通过 Mini Nutritional Assessment（MNA）评分进行评估。肌肉力量和体能水平通过标准化的身体功能测试和握力（HGS）进行评估。大多数参与者超重或肥胖（80%的 BMI>25）。糖尿病和高血压的患病率分别为 13%和 60%。与最高四分位 RHGS（12.0-15.1 千克）相比，BMI 调整后握力最低四分位（4.5-9.1 千克）的参与者糖尿病和高血压的患病率明显更高（分别为 20.7%和 5.3%，p<0.01；49.3%和 39.3%，p<0.01），且营养状况无显著差异。在握力较高的女性中，与糖尿病存在的关联明显较弱（OR 0.77；0.59-0.86 95%CI；p=0.002），独立于年龄、腹部肥胖和高血压的存在。RHGS 与所进行的大多数身体功能测试呈正相关。
RHGS 是肌肉力量的一种易于获得的测量指标，与超重活跃的老年女性糖尿病的存在独立相关。需要前瞻性研究来评估其预测价值，以识别有发生糖尿病风险的成年人。
