Chen Han, Chen Gang, Pan Yang, Zhu Yunxiao, Xiong Chaoyu, Chen Hualin, Yang Ziyi
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Department of Urology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China,
Urol Int. 2021;105(1-2):41-44. doi: 10.1159/000509472. Epub 2020 Aug 14.
Type II diabetes mellitus (DM) is a risk factor for urinary stones, but the pathogenesis remains unclear. The aim of our study was to present the distribution of stone components between DM and no DM group from a local stone center in China and to help the prevention department in decision-making.
We reviewed the records of patients with upper urinary stones attending our hospital from January 2015 to September 2018. The patients with complete information were divided into 2 groups: type II DM group (DM group) and without DM group (no DM group). The distribution of stone components was analyzed.
Two hundred twenty-two patients were complicated with DM, whereas 1,894 (89%) were not. Significant difference was found in the distribution of hypertension and BMI (p = 0, p = 0, respectively). Distribution of sex, age, and stone components did not differ between the 2 groups. By the binary logistic analysis, increasing age and sex seemed to be the main risk factors influencing the stone components. Only the calcium stone seemed to be free of the -impact from age and sex. Occurrence of hypertension is a single risk factor for calcium stone from our analysis. Presence of diabetes and increasing BMI was not found to be significantly associated with the risk for any stone component.
In a local district, DM might not be the main factor associated with an increased risk for uric acid stone formation or any stone component. We should also consider the local characteristics of the stone distribution.
2型糖尿病（DM）是尿路结石的一个危险因素，但其发病机制仍不清楚。我们研究的目的是展示来自中国当地一家结石中心的糖尿病组和非糖尿病组之间结石成分的分布情况，并帮助预防部门进行决策。
我们回顾了2015年1月至2018年9月在我院就诊的上尿路结石患者的记录。信息完整的患者被分为两组：2型糖尿病组（糖尿病组）和非糖尿病组（非糖尿病组）。分析结石成分的分布情况。
222例患者合并糖尿病，而1894例（89%）未合并糖尿病。在高血压和体重指数的分布上发现了显著差异（分别为p = 0，p = 0）。两组之间的性别、年龄和结石成分分布没有差异。通过二元逻辑分析，年龄增长和性别似乎是影响结石成分的主要危险因素。只有钙结石似乎不受年龄和性别的影响。根据我们的分析，高血压的发生是钙结石的单一危险因素。未发现糖尿病的存在和体重指数增加与任何结石成分的风险有显著关联。
在当地地区，糖尿病可能不是与尿酸结石形成风险增加或任何结石成分相关的主要因素。我们还应考虑结石分布的当地特征。
