McIntosh N
Department of Child Health, St George's Hospital, London.
Arch Dis Child. 1988 Feb;63(2):190-3. doi: 10.1136/adc.63.2.190.
We studied four infants whose mothers had had leaks of amniotic fluid for varying periods before birth. Three were associated with compression deformities. Oxygenation was achieved only by overriding the pressure limit safety devices on the resuscitation apparatus and ventilating after birth with high inflation pressures. In all cases the ventilation pressures had to be further increased for 12 hours but rapid improvement followed on the second day so that all four were spontaneously breathing air after a few days. It is postulated that collapse of the airways resulted from oligohydramnios, and that the resulting 'dry lungs' would only respond to high inflation pressures.
我们研究了四名婴儿，他们的母亲在分娩前不同时间段出现羊水渗漏。其中三例伴有压迫性畸形。仅通过超越复苏设备上的压力限制安全装置并在出生后用高充气压力进行通气才能实现氧合。在所有病例中，通气压力必须在12小时内进一步增加，但第二天病情迅速改善，以至于几天后所有四名婴儿均能自主呼吸空气。据推测，气道塌陷是由羊水过少导致的，由此产生的“肺不张”仅对高充气压力有反应。
