Jamil Johar, Zaman Khuzaifa, Ullah Saad, Ali Iftikhar
Department of Microbiology, University of Swabi, Swabi, Pakistan.
J Pak Med Assoc. 2020 Jul;70(7):1154-1158. doi: 10.5455/JPMA.9948.
To determine the prevalence of staphylococcus aureus in nasal carriers of healthy individuals and to evaluate their antibiotic susceptibility pattern.
The cross-sectional study was conducted at the University of Swabi, Swabi, Khyber Pakhtunkhwa, Pakistan, from October 2016 to April 2017, and comprised samples collected from nasal cavities of healthy students aged 19-26 years with the help of a sterile swab. For antibiotic susceptibility test, Kirby-Bauerdisc diffusion test was performed according to the guidelines of the Clinical and Laboratory Standards and Institute.
Of the 200 samples, staphylococcus aureus was detected in 41(20.5%). Among them, 27(65.85%) strains were isolated from male samples and 14(34.14%) from female samples. All (100%) strains were found to be sensitive to Cefoxitin and Linezolid, while all (100%) were resistant to Penicillin.
Staphylococcus aureus nasal colonization was found more in male than female isolates. Cefoxitin and Linezolid were the most effective drugs against the isolates, which were all resistant to Penicillin.
确定健康个体鼻腔携带者中金黄色葡萄球菌的流行情况,并评估其抗生素敏感性模式。
于2016年10月至2017年4月在巴基斯坦开伯尔-普赫图赫瓦省斯瓦比的斯瓦比大学开展了一项横断面研究,研究对象为借助无菌拭子从19至26岁健康学生鼻腔采集的样本。对于抗生素敏感性试验,按照临床和实验室标准协会的指南进行了 Kirby-Bauer 纸片扩散试验。
在200份样本中,检测出41份(20.5%)含有金黄色葡萄球菌。其中,27份(65.85%)菌株分离自男性样本,14份(34.14%)分离自女性样本。所有(100%)菌株对头孢西丁和利奈唑胺敏感,而所有(100%)菌株对青霉素耐药。
发现男性分离株中金黄色葡萄球菌鼻腔定植情况多于女性。头孢西丁和利奈唑胺是针对这些分离株最有效的药物,这些分离株均对青霉素耐药。