巴基斯坦白沙瓦部分医院耐抗生素金黄色葡萄球菌菌株的频率及比较

Frequency and comparison among antibiotic resistant Staphylococcus aureus strains in selected hospitals of Peshawar, Pakistan.

作者信息

Ahmad Sajjad, Ahmed Shehzad, Sabir Muhammad Shehryar, Khan Haqnawaz, Rehman Mubasher, Niaz Zeeshan

机构信息

Department of Microbiology, Hazara University, Mansehra, KPK, Pakistan.

Department of Microbiology, Hazara University Mansehra, KPK Pakistan.

出版信息

J Pak Med Assoc. 2020 Jul;70(7):1199-1202. doi: 10.5455/JPMA.26172.

DOI:10.5455/JPMA.26172

PMID:32799273

Abstract

OBJECTIVE

To assess and compare the frequency of antibiotic-resistant staphylococcus aureus strains.

METHODS

A retrospective study was conducted at the privately-owned Welfare Medical Laboratory, Peshawar, Pakistan, and comprised record related to the period between 07th February 2017 and 23rd March 2018 of patients referred for pus-testing from Khyber Teaching Hospital, Lady Reading Hospital and the Hayatabad Medical Complex. Pus samples were obtained from various parts of body with cotton swabs. The samples were cultured and the isolated staphylococcus aureus strains were analysed against selected antibiotics. The frequency of the isolated strains was tested and compared using Prism 7 software.

RESULTS

Of the 6780 samples, staphylococcus aureus was found in 4315(63.64%). Wild-type staphylococcus aureus strains were 2133(31.46%), followed by 825(12.16%) methicillin resistant, 792(11.68%) vancomycin intermediate, and 565(8.33%) vancomycin-resistant staphylococcus aureus strains. The isolated strains were significant (p<0.0001) for operated wounds, and non-significant (p=0.8915) for diabetic foot cases.

CONCLUSIONS

The frequency of antibiotic-resistant staphylococcu saureus strains was high.

摘要

目的

评估并比较耐抗生素金黄色葡萄球菌菌株的出现频率。

方法

在巴基斯坦白沙瓦的私立福利医学实验室进行了一项回顾性研究，研究对象为2017年2月7日至2018年3月23日期间从开伯尔教学医院、丽晶夫人医院和哈亚塔巴德医疗中心转诊来做脓液检测的患者记录。用棉签从身体各个部位获取脓液样本。对样本进行培养，并针对选定的抗生素对分离出的金黄色葡萄球菌菌株进行分析。使用Prism 7软件对分离菌株的出现频率进行检测和比较。

结果

在6780份样本中，发现4315份（63.64%）含有金黄色葡萄球菌。野生型金黄色葡萄球菌菌株有2133份（31.46%），其次是耐甲氧西林的825份（12.16%）、万古霉素中介的792份（11.68%）以及耐万古霉素的金黄色葡萄球菌菌株565份（8.33%）。分离出的菌株在手术伤口方面差异有统计学意义（p<0.0001），而在糖尿病足病例中差异无统计学意义（p=0.8915）。