School of Nursing, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
School of Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Clin Nurs Res. 2021 Mar;30(3):293-301. doi: 10.1177/1054773820951933. Epub 2020 Aug 17.
This study investigated the association between diabetes complications, diabetes distress, and depressive symptoms in patients with type 2 diabetes mellitus. A total of 600 patients with type 2 diabetes mellitus were included in this study. Data were collected using the Diabetes Distress Scale and the nine-item Patient Health Questionnaire. The results showed that both diabetes complications and diabetes distress were positively associated with depressive symptoms, and diabetes distress attenuated the association between diabetes complications and depressive symptoms. The Sobel test confirmed the mediating effect of diabetes distress. Patients with both diabetes complications and diabetes distress had a higher risk of depressive symptoms than those with diabetes complications or diabetes distress alone. This study indicates that the positive association between diabetes complications and depressive symptoms is persistent and mediated by diabetes distress, and the comorbidity of diabetes complications and diabetes distress has an additive interaction effect on depressive symptoms.
本研究旨在探讨 2 型糖尿病患者的糖尿病并发症、糖尿病困扰与抑郁症状之间的关系。共纳入 600 例 2 型糖尿病患者，采用糖尿病困扰量表和 9 项患者健康问卷收集数据。结果表明，糖尿病并发症和糖尿病困扰均与抑郁症状呈正相关，且糖尿病困扰减弱了糖尿病并发症与抑郁症状之间的关联。Sobel 检验证实了糖尿病困扰的中介作用。同时患有糖尿病并发症和糖尿病困扰的患者发生抑郁症状的风险高于仅患有糖尿病并发症或糖尿病困扰的患者。本研究表明，糖尿病并发症与抑郁症状之间的正相关关系是持续存在的，并由糖尿病困扰所介导，糖尿病并发症和糖尿病困扰的共病对抑郁症状具有相加交互作用。
