Zharkov V P, Iarygin V N, Gol'tsman L L
Biull Eksp Biol Med. 1988 Feb;105(2):216-9.
The possibility of pancreatic-islet embryonic implantation into the frontal chamber of the eye in Wistar rats has been demonstrated. The implantation was followed by the induction of alloxan diabetes. Clinical diabetic compensation has been shown in a number of experimental animals (maximum time of experiments--45 days). The formation of islet-like structures in the frontal chamber of the eye was confirmed microscopically. The structures contained B cells in their cytoplasm. Cellular differentiation leading to the appearance of functionally active endocrine cells has been noted in the implants.
已证实将胰岛胚胎植入Wistar大鼠眼前房的可能性。植入后诱发了四氧嘧啶糖尿病。在一些实验动物中显示出临床糖尿病代偿(实验最长时间为45天)。通过显微镜检查确认了眼前房内胰岛样结构的形成。这些结构的细胞质中含有B细胞。在植入物中已观察到导致功能活跃的内分泌细胞出现的细胞分化。