Bogensperger Christina, Cardini Benno, Oberhuber Rupert, Weissenbacher Annemarie, Gasteiger Silvia, Berchtold Valeria, Otarashvili Giorgi, Öfner Dietmar, Schneeberger Stefan
Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Department of Visceral, Transplant and Thoracic Surgery, Medical University of Innsbruck, Innsbruck, Austria.
Transplant Proc. 2020 Nov;52(9):2707-2710. doi: 10.1016/j.transproceed.2020.07.011. Epub 2020 Jul 22.
The coronavirus disease 2019 (COVID-19) pandemic has changed life on a global scale. The numbers of transplantations have plummeted as a result of fear of disease transmission, recipient coronavirus disease 2019 infection, priority shift, and resource limitations. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) complicates transplantation because donor testing, (re)allocation of limited resources, and recipient testing may exceed permissible ischemia times. Normothermic machine perfusion (NMP) helps safely prolong liver preservation up to 38 hours. Additional time is essential under the current circumstances. Here we present the case of a 29-year-old liver transplant recipient in whom prolonged liver preservation required for SARS-CoV-2 screening was accomplished through NMP. Donor and recipient test results for SARS-CoV-2 were negative, and intensive care unit capacity was eventually available. The surgical procedure and postoperative course were uneventful. NMP can extend preservation times in liver transplantation while awaiting SARS-CoV-2 test results and available intensive care unit capacity.
2019年冠状病毒病（COVID-19）大流行在全球范围内改变了生活。由于担心疾病传播、受者感染2019年冠状病毒病、优先事项转移和资源限制，移植手术数量大幅下降。严重急性呼吸综合征冠状病毒2（SARS-CoV-2）使移植手术变得复杂，因为供体检测、有限资源的（重新）分配以及受者检测可能超过允许的缺血时间。常温机器灌注（NMP）有助于将肝脏保存时间安全延长至38小时。在当前情况下，额外的时间至关重要。在此，我们介绍一例29岁的肝移植受者，通过NMP完成了SARS-CoV-2筛查所需的延长肝脏保存时间。供体和受者的SARS-CoV-2检测结果均为阴性，最终有了重症监护病房的床位。手术过程和术后病程顺利。NMP可以在等待SARS-CoV-2检测结果和有可用的重症监护病房床位时延长肝移植的保存时间。
