Clinica di Malattie Infettive, Fondazione IRCCS, Policlinico San Matteo, Pavia, Italy.
Am J Transplant. 2020 Jul;20(7):1882-1884. doi: 10.1111/ajt.15902. Epub 2020 May 10.
The clinical manifestation of COVID-19 can vary from an asymptomatic course to ARDS requiring invasive mechanical ventilation and extracorporeal membrane oxygenation. A kidney transplanted patient infected with SARS CoV-2 infection showed a mild disease despite immune suppression. It is possible that Immunosuppression can "be protective" as the cytokine storm is an important factor in the disease story. Despite the good outcome reported in the present case report, is remains of vital importance the solid organ transplant patients use precautions in order to avoid the infection.
COVID-19 的临床表现从无症状到需要有创机械通气和体外膜氧合的 ARDS 不等。尽管存在免疫抑制，但感染 SARS CoV-2 的肾移植患者表现出轻度疾病。免疫抑制可能是“保护性的”，因为细胞因子风暴是疾病发生的一个重要因素。尽管本病例报告报告了良好的结果，但实体器官移植患者仍需采取预防措施以避免感染，这一点至关重要。
