Stella Ariel E, Lima Thaís F, Moreira Cecília N, De Paula Eric M N
Universidade Federal de Jataí-UFJ, Jataí, Goiás State, Brazil.
Unifimes, Mineiros, Goiás State, Brazil.
Int J Microbiol. 2020 Aug 1;2020:2893027. doi: 10.1155/2020/2893027. eCollection 2020.
This study aims to detect () resistance in the veterinary hospital environment. are one of the components of the microbiota, and they may be present in patients in a veterinary hospital environment. Methicillin resistance is determined by a chromosomal gene (), which codes for modifications in the beta-lactam antibiotic receptor, where the penicillin-binding protein will have a low affinity for the antibiotic. Samples were collected through swabs of materials and equipment at the hospital. was identified in 7.6% (21/276) of the samples collected, and of the 21 strains isolated, 4 (19.0%) carried the gene. MRSA are all strains of that express the gene. Four strains harbor the gene; however, only two expressed the phenotypic resistance to cefoxitin and were characterized as MRSA. An isolate (strain 18) present on a patient care table was identified as methicillin-resistant with intermediate sensitivity to vancomycin (VISA). Our observations suggest the need for containment measures (good antisepsis practices) to avoid the possible transmission of resistant bacterial agents for the veterinary hospital environment.
本研究旨在检测兽医医院环境中的（）耐药性。（）是微生物群的组成部分之一，它们可能存在于兽医医院环境中的患者体内。甲氧西林耐药性由一个染色体基因（）决定，该基因编码β-内酰胺抗生素受体的修饰，其中青霉素结合蛋白对抗生素的亲和力较低。通过对医院的材料和设备进行拭子采样收集样本。在收集的7.6%（21/276）的样本中鉴定出了（），在分离出的21株菌株中，有4株（19.0%）携带（）基因。耐甲氧西林金黄色葡萄球菌是所有表达（）基因的（）菌株。有4株菌株携带（）基因；然而，只有2株对头孢西丁表现出表型耐药性，并被鉴定为耐甲氧西林金黄色葡萄球菌。在一张患者护理台上发现的一株分离株（菌株18）被鉴定为耐甲氧西林（），对万古霉素具有中度敏感性（万古霉素中介金黄色葡萄球菌）。我们的观察结果表明，需要采取控制措施（良好的防腐措施），以避免耐药细菌在兽医医院环境中可能的传播。
