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来自经电穿孔增强的疏脂性药物治疗的犬髓外浆细胞瘤的反应数据集。

Response dataset from canine extramedullary plasmacytoma treated with lipophobic drugs enhanced by electroporation.

作者信息

Dos Anjos Denner Santos, Rossi Ygor Amaral, Sierra Oscar Rodrigo, Bueno Cynthia Marchiori, De Nardi Andrigo Barboza, Fonseca-Alves Carlos Eduardo

机构信息

Department of Veterinary Clinic and Surgery, São Paulo State University (UNESP), Jaboticabal, São Paulo, Brazil.

Eletro-Onkovet Service.

出版信息

Data Brief. 2020 Jul 29;32:106085. doi: 10.1016/j.dib.2020.106085. eCollection 2020 Oct.

Abstract

Over the past 15 years, lipophobic drugs, such as bleomycin and cisplatin, have been used combined with electroporation, which promotes their uptake through the cell membrane. The present data describe general findings following electrochemotherapy and how plasmacytomas can respond to this technique. We will explain and illustrate specific outcomes during the remission process. The data presented here can be useful for researchers, veterinarians, and pet owners. Furthermore, the data could be useful for other cutaneous or oral tumors in which electrochemotherapy may be indicated. Interpretation of the data and outcomes may be found in the research article entitled "Outcome following curative-intent electrochemotherapy for extramedullary plasmocytoma in dogs - case reports ."

摘要

在过去15年里,亲脂性药物,如博来霉素和顺铂,已与电穿孔联合使用,电穿孔可促进它们通过细胞膜的摄取。目前的数据描述了电化学疗法后的一般发现以及浆细胞瘤对该技术的反应情况。我们将解释并说明缓解过程中的具体结果。这里呈现的数据对研究人员、兽医和宠物主人可能有用。此外,这些数据对于可能适用电化学疗法的其他皮肤或口腔肿瘤也可能有用。数据和结果的解读可在题为《犬髓外浆细胞瘤根治性电化学疗法后的结果——病例报告》的研究文章中找到。

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