Showa Pharmaceutical University, 3-3165 Higashi-Tamagawagakuen, Machida, Tokyo, 194-8543, Japan.
Laboratory of Genotoxicity, Faculty of Chemical and Biological Engineering, Hachinohe National College of Technology, 16-1 Tamonoki Uwanotai, Hachinohe, Aomori, 039-1192, Japan.
J Nat Med. 2021 Jan;75(1):167-172. doi: 10.1007/s11418-020-01443-4. Epub 2020 Aug 17.
Two new polyacetylene glycosides, kamiohnoyneosides A and B, were isolated from the flowers of edible Chrysanthemum "Kamiohno", along with a known polyacetylene glycoside and two known monoterpene glycosides. The structures of new compounds were elucidated on the basis of spectroscopic data. Kamiohnoyneoside A and three known compounds moderately inhibited formation of N-(carboxymethyl)lysine, one of the representative advanced glycation endproducts.
两种新的聚乙炔糖苷,kamiohnoyneosides A 和 B,从可食用的菊花“Kamiohno”的花中分离出来,同时分离出一种已知的聚乙炔糖苷和两种已知的单萜糖苷。新化合物的结构是根据光谱数据阐明的。Kamiohnoyneoside A 和三种已知化合物适度抑制了 N-(羧甲基)赖氨酸的形成,N-(羧甲基)赖氨酸是代表性的晚期糖基化终产物之一。