Associated Graduate Program in Physical Education UPE/UFPB, University of Pernambuco, Recife-PE, Brazil.
Laboratório de Pesquisa em Saúde e Desempenho Funcional (LABSED), University of Pernambuco, Petrolina-PE, Brazil.
J Alzheimers Dis. 2020;77(1):227-239. doi: 10.3233/JAD-200349.
Activities which simultaneously challenge both physical and cognitive function are promising strategies for promoting cognitive function.
To examine the effects of resistance exercise with instability and traditional resistance exercise compared with a health education control on cognitive function in older adults with cognitive complaints.
Sixty-seven participants were randomized to either 12 weeks of thrice-weekly resistance exercise (RE = 23), RE with instability (REI = 22), or a weekly health education control (CON = 22). At each training session, RE and REI participants performed seven exercises for three sets and 10-15 repetitions. REI participants performed each exercise using instability devices. The primary outcome was a composite score of global cognitive function. Secondary outcomes included composite scores for cognitive sub-domains and physical function.
Most participants were women (REI: 77%; RE = 78%; CON = 77%; mean age of 71 years), and did not need transport to the intervention site. At completion, compared with CON, REI and RE did not significantly improve on global cognition or each cognitive sub-domain. Both exercise groups improved on the timed up and go (REI - CON: -1.6 s, 95% CI: [-2.6, -0.5]; RE - CON: -1.4 s, 95% CI: [-2.4, -0.5) and 1-RM (REI - CON: 24 kg, 95% CI: [11, 36]; RE - CON: 25 kg, 95% CI: [12, 37]). An exploratory contrast showed that compared with RE, REI promote greater gains on global cognition (2.20, 95% CI: [0.10, 4.31]) and memory (1.34; 95% CI: [0.15, 2.54]).
REI did not substantially improve cognitive function but did promote physical function among older adults with cognitive complaints. However, compared with RE, REI improved global cognition and memory.
同时挑战身体和认知功能的活动是促进认知功能的有前途的策略。
研究与健康教育对照相比，抗阻运动加不稳定性训练与传统抗阻运动对有认知主诉的老年人认知功能的影响。
67 名参与者被随机分为每周 3 次的抗阻运动（RE=23 人）、抗阻运动加不稳定性训练（REI=22 人）或每周健康教育对照（CON=22 人）。在每次训练中，RE 和 REI 参与者进行 7 项运动，3 组，每组 10-15 次。REI 参与者使用不稳定性设备进行每项运动。主要结果是总体认知功能的综合评分。次要结果包括认知子域和身体功能的综合评分。
大多数参与者为女性（REI：77%；RE=78%；CON=77%；平均年龄 71 岁），不需要前往干预地点的交通工具。完成时，与 CON 相比，REI 和 RE 对整体认知或每个认知子域均无显著改善。两组运动组在计时起身和 1 次最大重复（REI- CON：-1.6 s，95%CI：[-2.6，-0.5]；RE- CON：-1.4 s，95%CI：[-2.4，-0.5）和 1-RM（REI- CON：24 kg，95%CI：[11，36]；RE- CON：25 kg，95%CI：[12，37]）方面有所改善。一项探索性对比表明，与 RE 相比，REI 对整体认知（2.20，95%CI：[0.10，4.31]）和记忆（1.34，95%CI：[0.15，2.54]）的改善更大。
REI 并未显著改善认知功能，但确实促进了有认知主诉的老年人的身体功能。然而，与 RE 相比，REI 改善了整体认知和记忆。
