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新冠疫情背景下的首例 ART 妊娠随访。

First follow-up of art pregnancies in the context of the COVID-19 outbreak.

机构信息

Reproductive Biology Unit CECOS, Paris-Saclay University, Antoine Béclère Hospital, APHP, Clamart 92140, France.

Reproductive Biology Unit CECOS, Paris-Saclay University, Antoine Béclère Hospital, APHP, Clamart 92140, France.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2020 Oct;253:71-75. doi: 10.1016/j.ejogrb.2020.07.050. Epub 2020 Jul 31.

DOI:10.1016/j.ejogrb.2020.07.050
PMID:32805629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7836367/
Abstract

OBJECTIVE

The aims of this study were to follow up the monitoring, health and anxiety from women who became pregnant after an embryo transfer or a intrauterine insemination during the COVID-19 epidemic in France STUDY DESIGN: This is a single centre, retrospective study from December 2019 to March 2020 based on a phone call interview using a specific questionnaire sheet specially developed for this study. Questionnaires from 104 pregnant women were completed and descriptive data are then analyzed.

RESULTS

Women with ongoing pregnancies (n = 88) did not change their physician visits. The COVID-19 outbreak has created no or few additional stresses for 77 % of pregnant women since the lockdown started. We report a miscarriage rate of 14.4 % (n = 15) and documented 10 patients (11.3 %) who had symptoms related to COVID-19. No severe symptoms and no hospitalization in intensive care unit were identified.

CONCLUSION

The epidemic context did not disrupt the medical monitoring of pregnancies and we did not recover an increased rate of miscarriage after ART. None of the patients who had COVID-related symptoms presented with severe clinical manifestations. Surprisingly, pregnant women were psychologically able to experience the lockdown.

摘要

目的

本研究旨在对法国 COVID-19 疫情期间接受胚胎移植或宫腔内人工授精后怀孕的女性进行监测、健康和焦虑状况随访。

研究设计

这是一项 2019 年 12 月至 2020 年 3 月基于专门为此项研究开发的特定问卷的电话访谈的单中心回顾性研究。共完成了 104 名孕妇的问卷,然后对描述性数据进行分析。

结果

继续妊娠的妇女(n=88)并未改变其就诊次数。自封锁开始以来,77%的孕妇报告 COVID-19 爆发未造成或仅造成少量额外压力。我们报告了 14.4%(n=15)的流产率,并记录了 10 名(11.3%)有 COVID-19 相关症状的患者。未发现严重症状,也未住院重症监护病房。

结论

疫情并未扰乱妊娠的医学监测,并且我们没有发现 ART 后流产率增加。有 COVID 相关症状的患者均未出现严重的临床表现。令人惊讶的是,孕妇在心理上能够承受封锁。

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